Protein Alignment CG11911 and PRSS27

DIOPT Version :10

• Sequence 1: NP_608518.1
• Gene: CG11911 / 33206
• FlyBaseID: FBgn0031249
• Length: 277
• Species: Drosophila melanogaster
• Sequence 2: NP_114154.1
• Gene: PRSS27 / 83886
• HGNCID: 15475
• Length: 290
• Species: Homo sapiens
• Alignment Length: 293
• Identity: 79/293 - (26%)
• Similarity: 126/293 - (43%)
• Gaps: 53/293 - (18%)

  Fly     6 VTLVIALVAAAQGAKLSDKLAKLVPSFATGFVINGTEAEPHSAPYIVSLATNYLKHSHICGGTLI 70
            |.|::.|...:|.||.:....:  |..... ::.|.:.:....|:.||:..|   .||.|||:||
Human     7 VPLLLLLCFGSQRAKAATACGR--PRMLNR-MVGGQDTQEGEWPWQVSIQRN---GSHFCGGSLI 65

  Fly    71 NKDWIVTAAHCI---SEPVGMSIIAGLHTRAEVDELTQQ---------RQVDFGRVHEKYTGGVG 123
            .:.|::|||||.   ||.....::.|..      :|.|.         |||:...:   |.|...
Human    66 AEQWVLTAAHCFRNTSETSLYQVLLGAR------QLVQPGPHAMYARVRQVESNPL---YQGTAS 121

  Fly   124 PYDIALLHVNESFIFNEWVQPATLPSREQVHEGETHLY--GWGQP-KSYIFSGAKTLQTVTTQIL 185
            ..|:||:.:.....|..::.|..||....:.|...:.:  |||.| :..:....:.||.:...|:
Human   122 SADVALVELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPII 186

  Fly   186 NYEECK-------EELPESAPIAESNICSSSLQQSKSACNGDSGGPLVVEFTNAPSELI------ 237
            :..:|.       |...:...|....:|:...:..|.||.||||||||.        |:
Human   187 DTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVC--------LVGQSWLQ 243

  Fly   238 -GIVSWGYIPCGLANMPSIYTKVSAYIDWITNI 269
             |::|||. .|...|.|.:|.:|:|:.:||..|
Human   244 AGVISWGE-GCARQNRPGVYIRVTAHHNWIHRI 275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11911	NP_608518.1	Tryp_SPc	37..266	CDD:214473	69/257 (27%)
PRSS27	NP_114154.1	Tryp_SPc	36..275	CDD:238113	71/259 (27%)