DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11911 and st14b

DIOPT Version :9

Sequence 1:	NP_608518.1	Gene:	CG11911 / 33206	FlyBaseID:	FBgn0031249	Length:	277	Species:	Drosophila melanogaster
Sequence 2:	XP_005161261.1	Gene:	st14b / 777629	ZFINID:	ZDB-GENE-061103-613	Length:	864	Species:	Danio rerio

Alignment Length:	253	Identity:	75/253 - (29%)
Similarity:	117/253 - (46%)	Gaps:	36/253 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 VINGTEAEPHSAPYIVSLATNYLK-HSHICGGTLINKDWIVTAAHCI--------SEPVGMSIIA 92
            ::.|.:::....|:.|||   ::| ..|:||.::|:..|:||||||:        |:.....:..
Zfish   625 IVGGKDSDEGEWPWQVSL---HMKTQGHVCGASVISNSWLVTAAHCVQDNDQFRYSQADQWEVYL 686

  Fly    93 GLHTRAEVDELTQQRQVDFGRV--HEKYTGGVGPYDIALLHVNESFIFNEWVQPATLPSREQVHE 155
            |||.:.|..:.||:..:   |:  |.:|.......||||:.::.....|:.:.|..||.
Zfish   687 GLHNQGETSKSTQRSVL---RIIPHPQYDHSSYDNDIALMELDSPVTLNQNIWPICLPD------ 742

  Fly   156 GETHLY---------GWGQPKSYIFSGAKTLQTVTTQILNYEECKEELPESAPIAESNICSSSLQ 211
             .||.:         |||:.:....:....||....:|:|...|.:.:.:.  |....||:..|.
Zfish   743 -PTHYFPAGKSVWITGWGKLREGSDAVPSVLQKAEVRIINSTVCSKLMDDG--ITPHMICAGVLS 804

  Fly   212 QSKSACNGDSGGPLVVEFTNAPSELIGIVSWGYIPCGLANMPSIYTKVSAYIDWITNI 269
            ....||.||||||:.....|....|.|:|||| ..||..|.|.:||:|:.|..||..|
Zfish   805 GGVDACQGDSGGPMSSIEGNGRMFLAGVVSWG-DGCGRRNRPGVYTRVTDYRSWIREI 861

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11911	NP_608518.1	Tryp_SPc	37..269	CDD:238113	74/251 (29%)
CG11911	NP_608518.1	Tryp_SPc	37..266	CDD:214473	72/248 (29%)
st14b	XP_005161261.1	SEA	92..180	CDD:279699
		CUB	233..342	CDD:238001
		CUB	351..457	CDD:238001
		LDLa	465..497	CDD:238060
		LDLa	499..533	CDD:238060
		LDLa	536..570	CDD:238060
		LDLa	578..613	CDD:238060
		Tryp_SPc	624..858	CDD:214473	72/248 (29%)
		Tryp_SPc	625..861	CDD:238113	74/251 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920