DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11911 and Prss36

DIOPT Version :9

Sequence 1:	NP_608518.1	Gene:	CG11911 / 33206	FlyBaseID:	FBgn0031249	Length:	277	Species:	Drosophila melanogaster
Sequence 2:	XP_017167884.1	Gene:	Prss36 / 77613	MGIID:	1924863	Length:	863	Species:	Mus musculus

Alignment Length:	263	Identity:	74/263 - (28%)
Similarity:	113/263 - (42%)	Gaps:	56/263 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 VINGTEAEPHSAPYIVSLATNYLKHSHICGGTLINKDWIVTAAHCI-----SEPVG-MSIIAGLH 95
            ::.|::|.|.:.|:.|||   :....|||||:||...|:::||||.     .||.. :|::.|:|
Mouse    48 IVGGSDAHPGTWPWQVSL---HQGGGHICGGSLIAPSWVLSAAHCFVTNGTLEPADELSVLLGVH 109

  Fly    96 TRAEVDELTQQRQVDFGRVHEKYTGGVGPYDIALLHVNESFIFNEWVQPATLPSREQVHEGETHL 160
            ::....|....|.|....:.:.|:......|:|||.:.........|:|..||.       .:||
Mouse   110 SQDGPLEGAHMRSVATILIPDNYSTVELGADLALLRLASPAKLGPSVRPVCLPR-------ASHL 167

  Fly   161 Y---------GWGQ-------PKSYIFSGAKTLQTVTTQILNYEECKEELPESAP------IAES 203
            :         |||.       |..::      ||.|..::|....|:.......|      :...
Mouse   168 FAHGTACWATGWGDVQEAVPLPLPWV------LQEVELRLLGEAACQCLYSRPGPFNLTFQLLPG 226

  Fly   204 NICSSSLQQSKSACNGDSGGPLVVE-----FTNAPSELIGIVSWGYIPCGLANMPSIYTKVSAYI 263
            .:|:......:..|.||||||||.|     |      |.||.|:|: .||..|.|.::|.|:.|.
Mouse   227 MLCAGYPAGRRDTCQGDSGGPLVCEDGGRWF------LAGITSFGF-GCGRRNRPGVFTAVAPYE 284

  Fly   264 DWI 266
            .||
Mouse   285 SWI 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11911	NP_608518.1	Tryp_SPc	37..269	CDD:238113	74/263 (28%)
CG11911	NP_608518.1	Tryp_SPc	37..266	CDD:214473	72/261 (28%)
Prss36	XP_017167884.1	Tryp_SPc	48..290	CDD:238113	74/263 (28%)
		Tryp_SPc	331..532	CDD:389826
		Tryp_SPc	607..789	CDD:389826
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010