DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11911 and Prss44

DIOPT Version :9

Sequence 1:	NP_608518.1	Gene:	CG11911 / 33206	FlyBaseID:	FBgn0031249	Length:	277	Species:	Drosophila melanogaster
Sequence 2:	NP_683742.2	Gene:	Prss44 / 73336	MGIID:	1920586	Length:	372	Species:	Mus musculus

Alignment Length:	260	Identity:	81/260 - (31%)
Similarity:	127/260 - (48%)	Gaps:	43/260 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 PSFATGF----VINGTEAEPHSAPYIVSLATNYLKHSHICGGTLINKDWIVTAAHCISEPVGMSI 90
            |:.|.|.    ::.|..|.....|:.|||..:   ..|||||:||:|.|::|||||:...:..::
Mouse   101 PTSACGHRTARIVGGRPAPARKWPWQVSLQVH---KQHICGGSLISKWWVITAAHCVYGHLDYAV 162

  Fly    91 IAG---LHTRAEV-----DELTQQRQVDFGRVHEKYTGGVGPYDIALLHVNESFIFNEWVQPATL 147
            ..|   |.::..|     |.:..|   ||..:....      :||||:.:.....::..:||..:
Mouse   163 FMGDADLWSKRPVRIPVQDIIVHQ---DFSMMRTVV------HDIALVLLAFPVNYSVNIQPVCI 218

  Fly   148 PSREQVHEGETHLY--GWG----QPKSYIFSGAKTLQTVTTQILNYEECKEELPE-----SAPIA 201
            |.:..:.:..|..:  |||    |.:|     ::.||.:...|:.:|:|.:.|.:     ...:.
Mouse   219 PEKSFLVQPGTLCWVTGWGKVLEQGRS-----SRILQEIELNIIRHEKCNQILKDIMGNIFTLVQ 278

  Fly   202 ESNICSSSLQQSKSACNGDSGGPLVVEFTNAPSELIGIVSWGYIPCGLANMPSIYTKVSAYIDWI 266
            |..:|..: ::...||.||||||||.|| |.....:|||||| :.||....|.:||:||.|.|||
Mouse   279 EGGVCGYN-EKGGDACQGDSGGPLVCEF-NKTWVQVGIVSWG-LGCGRIGYPGVYTEVSYYRDWI 340

Fly 267 266
Mouse 341 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11911	NP_608518.1	Tryp_SPc	37..269	CDD:238113	78/249 (31%)
CG11911	NP_608518.1	Tryp_SPc	37..266	CDD:214473	76/247 (31%)
Prss44	NP_683742.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	31..72
		Tryp_SPc	111..340	CDD:214473	76/248 (31%)
		Tryp_SPc	112..340	CDD:238113	76/247 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920