DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG11911 and Tmprss6

DIOPT Version :9

Sequence 1:NP_608518.1 Gene:CG11911 / 33206 FlyBaseID:FBgn0031249 Length:277 Species:Drosophila melanogaster
Sequence 2:NP_082178.2 Gene:Tmprss6 / 71753 MGIID:1919003 Length:811 Species:Mus musculus


Alignment Length:262 Identity:76/262 - (29%)
Similarity:114/262 - (43%) Gaps:58/262 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    37 VINGTEAEPHSAPYIVSLATNYLKHSHICGGTLINKDWIVTAAHCISE-----PVGMSIIAG--- 93
            ::.||.:.....|:..||   .::..|||||.||...|::|||||..|     |...::..|   
Mouse   577 IVGGTVSSEGEWPWQASL---QIRGRHICGGALIADRWVITAAHCFQEDSMASPKLWTVFLGKMR 638

  Fly    94 -----------------LHTRAEVDELTQQRQVDFGRVHEKYTGGVGPYDIALLHVNESFIFNEW 141
                             ||...|.|.            |:        ||:|||.::...:::..
Mouse   639 QNSRWPGEVSFKVSRLFLHPYHEEDS------------HD--------YDVALLQLDHPVVYSAT 683

  Fly   142 VQPATLPSREQVHEGETHLY--GWGQPKSYIFSG--AKTLQTVTTQILNYEECKEELPESAPIAE 202
            |:|..||:|....|...|.:  |||..:.   .|  :.|||.|..|::..:.|.|..  ...::.
Mouse   684 VRPVCLPARSHFFEPGQHCWITGWGAQRE---GGPVSNTLQKVDVQLVPQDLCSEAY--RYQVSP 743

  Fly   203 SNICSSSLQQSKSACNGDSGGPLVVEFTNAPSELIGIVSWGYIPCGLANMPSIYTKVSAYIDWIT 267
            ..:|:...:..|.||.||||||||....:....|.|:|||| :.||..|...:||:|:..|:||.
Mouse   744 RMLCAGYRKGKKDACQGDSGGPLVCREPSGRWFLAGLVSWG-LGCGRPNFFGVYTRVTRVINWIQ 807

  Fly   268 NI 269
            .:
Mouse   808 QV 809

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11911NP_608518.1 Tryp_SPc 37..269 CDD:238113 76/260 (29%)
Tryp_SPc 37..266 CDD:214473 74/257 (29%)
Tmprss6NP_082178.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..48
SEA 88..185 CDD:279699
LDLa 459..489 CDD:238060
LDLa 495..525 CDD:238060
Ldl_recept_a 529..566 CDD:278486
Tryp_SPc 576..806 CDD:214473 74/257 (29%)
Tryp_SPc 577..809 CDD:238113 76/260 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D433637at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.010

Return to query results.
Submit another query.