DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11911 and C1R

DIOPT Version :9

Sequence 1:	NP_608518.1	Gene:	CG11911 / 33206	FlyBaseID:	FBgn0031249	Length:	277	Species:	Drosophila melanogaster
Sequence 2:	NP_001341275.1	Gene:	C1R / 715	HGNCID:	1246	Length:	719	Species:	Homo sapiens

Alignment Length:	254	Identity:	72/254 - (28%)
Similarity:	107/254 - (42%)	Gaps:	44/254 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 VINGTEAEPHSAPYIVSLATNYLKHSHICGGTLINKDWIVTAAHCI-------SEPVGMSIIAGL 94
            :|.|.:|:..:.|:  .:.||.  |.. .||.|:...||:||||.:       .....:.:..|
Human   478 IIGGQKAKMGNFPW--QVFTNI--HGR-GGGALLGDRWILTAAHTLYPKEHEAQSNASLDVFLG- 536

  Fly    95 HTRAEVDELTQQ-----RQVDFGRVHEKYTGGVGPY----DIALLHVNESFIFNEWVQPATLPSR 150
            ||  .|:||.:.     |:|.   ||..|..... |    |||||.:..|......:.|..||..
Human   537 HT--NVEELMKLGNHPIRRVS---VHPDYRQDES-YNFEGDIALLELENSVTLGPNLLPICLPDN 595

  Fly   151 EQVHE----GETHLYGWGQPKSYIFSGAKTLQTVTTQILNYEECKEEL---PESAPIAESNICSS 208
            :..::    |  ::.|:|..:..|   |..|:.|...:.|.:.|:..|   ......:::..|:.
Human   596 DTFYDLGLMG--YVSGFGVMEEKI---AHDLRFVRLPVANPQACENWLRGKNRMDVFSQNMFCAG 655

  Fly   209 SLQQSKSACNGDSGGPLVVEFTNAPSEL-IGIVSWGYIPCGLANMPSIYTKVSAYIDWI 266
            .....:.||.|||||...|...|....: .||||||   .|.:.....||||..|:|||
Human   656 HPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWG---IGCSRGYGFYTKVLNYVDWI 711

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11911	NP_608518.1	Tryp_SPc	37..269	CDD:238113	72/254 (28%)
CG11911	NP_608518.1	Tryp_SPc	37..266	CDD:214473	70/252 (28%)
C1R	NP_001341275.1	CUB	41..152	CDD:214483
		FXa_inhibition	175..203	CDD:317114
		CUB	207..316	CDD:278839
		Sushi	323..385	CDD:306569
		Sushi	390..461	CDD:306569
		Tryp_SPc	477..711	CDD:214473	70/252 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910