Protein Alignment CG11911 and PRSS22

DIOPT Version :10

• Sequence 1: NP_608518.1
• Gene: CG11911 / 33206
• FlyBaseID: FBgn0031249
• Length: 277
• Species: Drosophila melanogaster
• Sequence 2: XP_054169579.1
• Gene: PRSS22 / 64063
• HGNCID: 14368
• Length: 425
• Species: Homo sapiens
• Alignment Length: 244
• Identity: 77/244 - (31%)
• Similarity: 117/244 - (47%)
• Gaps: 16/244 - (6%)

  Fly    37 VINGTEAEPHSAPYIVSLATNYLKHSHICGGTLINKDWIVTAAHC----ISEPVGMSIIAGLHTR 97
            |:.|.::.....|:|||:..|   .:|.|.|:|:...|::|||||    :::|...|::.|....
Human   158 VVGGEDSTDSEWPWIVSIQKN---GTHHCAGSLLTSRWVITAAHCFKDNLNKPYLFSVLLGAWQL 219

  Fly    98 AEVDELTQQRQVDFGRVHEKYTGGVGP-YDIALLHVNESFIFNEWVQPATLPSREQVHEGETHLY 161
            ......:|:..|.:...|..|:...|. .||||:.:..|..|:|.|.|..||.........||.:
Human   220 GNPGSRSQKVGVAWVEPHPVYSWKEGACADIALVRLERSIQFSERVLPICLPDASIHLPPNTHCW 284

  Fly   162 --GWGQPKSYI-FSGAKTLQTVTTQILNYEECKEELPESA---PIAESNICSSSLQQSKSACNGD 220
              |||..:..: ....:|||.:...|::.|.|.......|   ||.|..:|:..|:..:.||.||
Human   285 ISGWGSIQDGVPLPHPQTLQKLKVPIIDSEVCSHLYWRGAGQGPITEDMLCAGYLEGERDACLGD 349

  Fly   221 SGGPLVVEFTNAPSELIGIVSWGYIPCGLANMPSIYTKVSAYIDWITNI 269
            |||||:.:...| ..|.||:|||. .|...|.|.:|..:||:..|:..|
Human   350 SGGPLMCQVDGA-WLLAGIISWGE-GCAERNRPGVYISLSAHRSWVEKI 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11911	NP_608518.1	Tryp_SPc	37..266	CDD:214473	75/239 (31%)
PRSS22	XP_054169579.1	Tryp_SPc	158..396	CDD:238113	76/242 (31%)