Protein Alignment CG11911 and KLK10

DIOPT Version :10

• Sequence 1: NP_608518.1
• Gene: CG11911 / 33206
• FlyBaseID: FBgn0031249
• Length: 277
• Species: Drosophila melanogaster
• Sequence 2: NP_002767.2
• Gene: KLK10 / 5655
• HGNCID: 6358
• Length: 276
• Species: Homo sapiens
• Alignment Length: 287
• Identity: 86/287 - (29%)
• Similarity: 127/287 - (44%)
• Gaps: 52/287 - (18%)

  Fly    13 VAAAQGAKLSDKLAKLVP--------SFATGFVINGTEAEPH---------SAPYIVSLATNYLK 60
            ::||.||:   .||||:|        :.|.....|.|..:|.         |.|:.|||......
Human     8 LSAASGAR---ALAKLLPLLMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQVSLFNGLSF 69

  Fly    61 HSHICGGTLINKDWIVTAAHCISEPVGMSIIAGLHTRAEVDEL-----TQQRQVDFGRVHEKYTG 120
            |   |.|.|:::.|::|||||.::|        |..|...|.|     .|.|:.....||.||..
Human    70 H---CAGVLVDQSWVLTAAHCGNKP--------LWARVGDDHLLLLQGEQLRRTTRSVVHPKYHQ 123

  Fly   121 GVGP--------YDIALLHVNESFIFNEWVQPATLPSREQVHEGETHLYGWGQPKSYIFSGAKTL 177
            |.||        :|:.||.:....:....|:...||.|......:..:.|||...:......|.|
Human   124 GSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKGL 188

  Fly   178 QTVTTQILNYEECKEELPESAPIAESNICSSSLQQSKSACNGDSGGPLVVEFTNAPSELIGIVSW 242
            ...:..||:.:||:...|   .:..:|:..:.|.:.:..|..|||||||.:.|     |.||:||
Human   189 TCSSITILSPKECEVFYP---GVVTNNMICAGLDRGQDPCQSDSGGPLVCDET-----LQGILSW 245

  Fly   243 GYIPCGLANMPSIYTKVSAYIDWITNI 269
            |..|||.|..|::||::..|:.||..:
Human   246 GVYPCGSAQHPAVYTQICKYMSWINKV 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11911	NP_608518.1	Tryp_SPc	37..266	CDD:214473	74/250 (30%)
KLK10	NP_002767.2	Tryp_SPc	49..272	CDD:238113	73/241 (30%)