Protein Alignment CG11911 and PRSS1

DIOPT Version :10

• Sequence 1: NP_608518.1
• Gene: CG11911 / 33206
• FlyBaseID: FBgn0031249
• Length: 277
• Species: Drosophila melanogaster
• Sequence 2: NP_002760.1
• Gene: PRSS1 / 5644
• HGNCID: 9475
• Length: 247
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 85/270 - (31%)
• Similarity: 126/270 - (46%)
• Gaps: 34/270 - (12%)

  Fly     8 LVIALVAAAQGAKLSDKLAKLVPSFATGFVINGTEAEPHSAPYIVSLATNYLKHSHICGGTLINK 72
            |::..||||..|...|          ...::.|...|.:|.||.|||.:.|    |.|||:|||:
Human     5 LILTFVAAALAAPFDD----------DDKIVGGYNCEENSVPYQVSLNSGY----HFCGGSLINE 55

  Fly    73 DWIVTAAHCISEPVGMSIIAGLHTRAEVDELTQQRQVDFGRV--HEKYTGGVGPYDIALLHVNES 135
            .|:|:|.||....:.:.:  |.| ..||.|..:| .::..::  |.:|.......||.|:.::..
Human    56 QWVVSAGHCYKSRIQVRL--GEH-NIEVLEGNEQ-FINAAKIIRHPQYDRKTLNNDIMLIKLSSR 116

  Fly   136 FIFNEWVQPATLPSREQVHEGETHLYGWGQPKSYIFSGA---KTLQTVTTQILNYEECKEELPES 197
            .:.|..|...:||:.......:..:.|||...|   |||   ..||.:...:|:..:|:...|
Human   117 AVINARVSTISLPTAPPATGTKCLISGWGNTAS---SGADYPDELQCLDAPVLSQAKCEASYP-- 176

  Fly   198 APIAESNICSSSLQQSKSACNGDSGGPLVVEFTNAPSELIGIVSWGYIPCGLANMPSIYTKVSAY 262
            ..|..:..|...|:..|.:|.||||||:|..     .:|.|:|||| ..|...|.|.:||||..|
Human   177 GKITSNMFCVGFLEGGKDSCQGDSGGPVVCN-----GQLQGVVSWG-DGCAQKNKPGVYTKVYNY 235

  Fly   263 IDWITNIQSA 272
            :.||.|..:|
Human   236 VKWIKNTIAA 245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11911	NP_608518.1	Tryp_SPc	37..266	CDD:214473	74/233 (32%)
PRSS1	NP_002760.1	Tryp_SPc	23..239	CDD:214473	74/234 (32%)