Protein Alignment CG11911 and PROC

DIOPT Version :10

• Sequence 1: NP_608518.1
• Gene: CG11911 / 33206
• FlyBaseID: FBgn0031249
• Length: 277
• Species: Drosophila melanogaster
• Sequence 2: XP_024308771.1
• Gene: PROC / 5624
• HGNCID: 9451
• Length: 556
• Species: Homo sapiens
• Alignment Length: 297
• Identity: 93/297 - (31%)
• Similarity: 133/297 - (44%)
• Gaps: 56/297 - (18%)

  Fly    14 AAAQGAKLSDKLAKLVPS--FATG--------------------------FVINGTEAEPHSAPY 50
            :.|.|.||.|.|.:..|:  |..|                          .:|:|.......:|:
Human   256 SCAPGYKLGDDLLQCHPAVKFPCGRPWKRMEKKRSHLKRDTEDQEDQVDPRLIDGKMTRRGDSPW 320

  Fly    51 IVSLATNYLKHSHICGGTLINKDWIVTAAHCISEPVGMSIIAGLH--TRAEVDELTQQRQVDFGR 113
            .|.|..:  |....||..||:..|::|||||:.|...:.:..|.:  .|.|..||....:..|
Human   321 QVVLLDS--KKKLACGAVLIHPSWVLTAAHCMDESKKLLVRLGEYDLRRWEKWELDLDIKEVF-- 381

  Fly   114 VHEKYTGGVGPYDIALLHVNESFIFNEWVQPATLP-----SREQVHEG-ETHLYGWGQPKSYIFS 172
            ||..|:......||||||:.:....::.:.|..||     .||....| ||.:.|||    |..|
Human   382 VHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPDSGLAERELNQAGQETLVTGWG----YHSS 442

  Fly   173 GAKTLQTVTTQILNY--------EECKEELPESAPIAESNICSSSLQQSKSACNGDSGGPLVVEF 229
            ..|..:...|.:||:        .||.|.:  |..::|:.:|:..|...:.||.||||||:|..|
Human   443 REKEAKRNRTFVLNFIKIPVVPHNECSEVM--SNMVSENMLCAGILGDRQDACEGDSGGPMVASF 505

  Fly   230 TNAPSELIGIVSWGYIPCGLANMPSIYTKVSAYIDWI 266
             :....|:|:||||. .|||.:...:|||||.|:|||
Human   506 -HGTWFLVGLVSWGE-GCGLLHNYGVYTKVSRYLDWI 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11911	NP_608518.1	Tryp_SPc	37..266	CDD:214473	82/244 (34%)
PROC	XP_024308771.1	GLA	85..148	CDD:214503
		EGF_CA	162..193	CDD:238011
		FXa_inhibition	235..270	CDD:464251	6/13 (46%)
		Tryp_SPc	308..543	CDD:238113	84/245 (34%)