DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11911 and Prss53

DIOPT Version :9

Sequence 1:	NP_608518.1	Gene:	CG11911 / 33206	FlyBaseID:	FBgn0031249	Length:	277	Species:	Drosophila melanogaster
Sequence 2:	XP_006230384.1	Gene:	Prss53 / 499270	RGDID:	1566127	Length:	591	Species:	Rattus norvegicus

Alignment Length:	230	Identity:	66/230 - (28%)
Similarity:	102/230 - (44%)	Gaps:	33/230 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 LKHSH---ICGGTLINKDWIVTAAHCISEPVGMSII----AGLHTRAEVDELTQQRQVDFGRVHE 116
            ||| |   .|||.|:::..::|||||.   :|...:    .||....|...|.|.      .:|.
  Rat   357 LKH-HGKLACGGALVSEVVVLTAAHCF---IGRQTLEEWSVGLGAGPEEWGLKQL------ILHG 411

  Fly   117 KYTGGVGPYDIALLHVNESFIFNEWVQPATLP-SREQVHEGETHLYGW--GQPKSYIFSGAKTLQ 178
            .||...|.:|:|.|.:.:.......::|..|| :..::.:||   :||  |..:.   :|.....
  Rat   412 AYTHPEGGHDVAFLLLAQPVTLGPGLRPLCLPYADHRLPDGE---HGWVLGLTRE---AGINHPH 470

  Fly   179 TVTTQILNYEECKEELPES----APIAESNICSSSLQQSKSACNGDSGGPLVVEFTNAPSELIGI 239
            ||...:|....|..:...|    .||....||::.:.:... |.|.||.|||.|. .....|.|:
  Rat   471 TVPVTVLGPMACSRQHAASGSTGVPILPGMICTTVVGEPPH-CEGLSGAPLVHEI-RGTWFLAGL 533

  Fly   240 VSWGYIPCGLANMPSIYTKVSAYIDWITNIQSAYY 274
            .|:|....|.|. |:::..:|||.||::|:....|
  Rat   534 HSFGDTCQGSAK-PAVFAALSAYEDWVSNLDWQVY 567

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11911	NP_608518.1	Tryp_SPc	37..269	CDD:238113	64/223 (29%)
CG11911	NP_608518.1	Tryp_SPc	37..266	CDD:214473	63/220 (29%)
Prss53	XP_006230384.1	Tryp_SPc	45..310	CDD:238113
Prss53	XP_006230384.1	Tryp_SPc	341..561	CDD:238113	64/222 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010