Protein Alignment CG11911 and KLK12

DIOPT Version :10

• Sequence 1: NP_608518.1
• Gene: CG11911 / 33206
• FlyBaseID: FBgn0031249
• Length: 277
• Species: Drosophila melanogaster
• Sequence 2: NP_062544.1
• Gene: KLK12 / 43849
• HGNCID: 6360
• Length: 254
• Species: Homo sapiens
• Alignment Length: 262
• Identity: 76/262 - (29%)
• Similarity: 118/262 - (45%)
• Gaps: 36/262 - (13%)

  Fly     4 ITVTLVIALVAAAQGAKLSDKLAKLVPSFATGFVINGTEAEPHSAPYIVSLATNYLKHSHICGGT 68
            :::.|::.::..:|.              ||..:.||||...:|.|:.|.|   :...|..|||.
Human     3 LSIFLLLCVLGLSQA--------------ATPKIFNGTECGRNSQPWQVGL---FEGTSLRCGGV 50

  Fly    69 LINKDWIVTAAHCISEPVGMSIIAGLHTRAEVDELTQQRQVDFGRVHEKYTGG--VGPYDIALLH 131
            ||:..|::|||||......:.:  |.|:.:::|...|.|...|...|..|.|.  ...:|:.||.
Human    51 LIDHRWVLTAAHCSGSRYWVRL--GEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLR 113

  Fly   132 VNESFIFNEWVQPATLPSREQVHEGETHLYGWG---QPKSYIFSGAKTLQTVTTQILNYEECKEE 193
            :.........|||..||:.......|.|:.|||   .|::..   ...||.:...|:::..|...
Human   114 LRLPVRVTSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPF---PDLLQCLNLSIVSHATCHGV 175

  Fly   194 LPESAPIAESNICSSSLQQSKSACNGDSGGPLVVEFTNAPSELIGIVSWGYI-PCGLANMPSIYT 257
            .|  ..|..:.:|:..: ..:.||.||||||||     ....|.|:||||.: |||...:|.:||
Human   176 YP--GRITSNMVCAGGV-PGQDACQGDSGGPLV-----CGGVLQGLVSWGSVGPCGQDGIPGVYT 232

  Fly   258 KV 259
            .:
Human   233 YI 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11911	NP_608518.1	Tryp_SPc	37..266	CDD:214473	72/229 (31%)
KLK12	NP_062544.1	Tryp_SPc	22..236	CDD:238113	72/229 (31%)