DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG11911 and KLK14

DIOPT Version :9

Sequence 1:NP_608518.1 Gene:CG11911 / 33206 FlyBaseID:FBgn0031249 Length:277 Species:Drosophila melanogaster
Sequence 2:NP_001298111.2 Gene:KLK14 / 43847 HGNCID:6362 Length:251 Species:Homo sapiens


Alignment Length:271 Identity:77/271 - (28%)
Similarity:111/271 - (40%) Gaps:32/271 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MKLITVTLVIALVAAAQGAKLSDKLAKLVPSFATGFVINGTEAEPHSAPYIVSLATNYLKHSHIC 65
            |.|:...|.:..:|..|..:..:|            :|.|......|.|:..:|... .:...:|
Human     1 MFLLLTALQVLAIAMTQSQEDENK------------IIGGHTCTRSSQPWQAALLAG-PRRRFLC 52

  Fly    66 GGTLINKDWIVTAAHCISEPVGMSIIAGLHTRAEVDELTQQ-----RQVDFGRVHEKYTGGVGPY 125
            ||.|::..|::||||| ..|: :.:..|.|..... |.|||     |||    .|..|.......
Human    53 GGALLSGQWVITAAHC-GRPI-LQVALGKHNLRRW-EATQQVLRVVRQV----THPNYNSRTHDN 110

  Fly   126 DIALLHVNESFIFNEWVQPATLPSREQVHEGETHLYGWGQPKSYIFSGAKTLQTVTTQILNYEEC 190
            |:.||.:.:.......|:|..:............:.|||...|.|.....:||.|...|...|.|
Human   111 DLMLLQLQQPARIGRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVC 175

  Fly   191 KEELPESAPIAESNICSSSLQQSKSACNGDSGGPLVVEFTNAPSELIGIVSWGYIPCGLANMPSI 255
            ::..|.:  |....:|:...|..|.:|.||||||||..     .:|.|:||||...|.|...|.:
Human   176 QKAYPRT--ITPGMVCAGVPQGGKDSCQGDSGGPLVCR-----GQLQGLVSWGMERCALPGYPGV 233

  Fly   256 YTKVSAYIDWI 266
            ||.:..|..||
Human   234 YTNLCKYRSWI 244

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11911NP_608518.1 Tryp_SPc 37..269 CDD:238113 71/235 (30%)
Tryp_SPc 37..266 CDD:214473 69/233 (30%)
KLK14NP_001298111.2 Tryp_SPc 25..247 CDD:238113 71/235 (30%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D433637at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

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