DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11911 and Tmprss9

DIOPT Version :9

Sequence 1:	NP_608518.1	Gene:	CG11911 / 33206	FlyBaseID:	FBgn0031249	Length:	277	Species:	Drosophila melanogaster
Sequence 2:	XP_006513905.2	Gene:	Tmprss9 / 432478	MGIID:	3612246	Length:	1342	Species:	Mus musculus

Alignment Length:	253	Identity:	83/253 - (32%)
Similarity:	118/253 - (46%)	Gaps:	27/253 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 ATGFVINGTEAEPHSAPYIVSLATNYLKHSHICGGTLINKDWIVTAAHCISE---PVGMSIIAG- 93
            :.|.::.|.||.|...|:.|||..|   |.|.||.|:|...|:|:||||.:|   |...:..||
Mouse   452 SAGRIVGGVEAAPGEFPWQVSLREN---HEHFCGATIIGARWLVSAAHCFNEFQDPAQWAAQAGS 513

  Fly    94 LHTRAEVDELTQQRQVDFGRVHEKYTGGVGPYDIALLHVNESFIFNEWVQPATLPSREQVHEGET 158
            :|.........:.|.:...: |..|......:|:|:|.:.....|..:||||.||:       .|
Mouse   514 VHLSGSEASAVRTRVLRIAK-HPAYDADTADFDVAVLELARPLPFGRYVQPACLPA-------AT 570

  Fly   159 HLY---------GWGQPKSYIFSGAKTLQTVTTQILNYEECKEELPESAPIAESNICSSSLQQSK 214
            |::         |||..|.......:.||..|.::|:...|......|  :.:..:|:..|....
Mouse   571 HVFPPGKKCLISGWGYLKEDFLVKPEVLQKATVELLDQSLCSSLYGHS--LTDRMVCAGYLDGKV 633

  Fly   215 SACNGDSGGPLVVEFTNAPSELIGIVSWGYIPCGLANMPSIYTKVSAYIDWITNIQSA 272
            .:|.||||||||.|..:....|.|||||| |.|..|..|.:||:|:...|||..:.||
Mouse   634 DSCQGDSGGPLVCEEPSGRFFLAGIVSWG-IGCAEARRPGVYTRVTRLRDWILEVTSA 690

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11911	NP_608518.1	Tryp_SPc	37..269	CDD:238113	80/244 (33%)
CG11911	NP_608518.1	Tryp_SPc	37..266	CDD:214473	78/241 (32%)
Tmprss9	XP_006513905.2	SEA	285..365	CDD:366610
		LDLa	407..442	CDD:238060
		Tryp_SPc	455..684	CDD:214473	78/242 (32%)
		Tryp_SPc	756..984	CDD:214473
		Tryp_SPc	1085..1336	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920