DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG11911 and KLKB1

DIOPT Version :9

Sequence 1:NP_608518.1 Gene:CG11911 / 33206 FlyBaseID:FBgn0031249 Length:277 Species:Drosophila melanogaster
Sequence 2:XP_011530232.1 Gene:KLKB1 / 3818 HGNCID:6371 Length:649 Species:Homo sapiens


Alignment Length:243 Identity:78/243 - (32%)
Similarity:119/243 - (48%) Gaps:25/243 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    37 VINGTEAEPHSAPYIVSLATNYLKHSHICGGTLINKDWIVTAAHCISEPVGM------SIIAGLH 95
            ::.||.:.....|:.|||........|:|||:||...|::|||||..   |:      .|.:|:.
Human   402 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFD---GLPLQDVWRIYSGIL 463

  Fly    96 TRAEVDELTQQRQVDFGRVHEKYTGGVGPYDIALLHVNESFIFNEWVQPATLPSREQVHEGETHL 160
            ..:::.:.|...|:....:|:.|....|.:||||:.:.....:.|:.:|..|||:.......|:.
Human   464 NLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNC 528

  Fly   161 Y--GWGQPKSYIFSGAK-----TLQTVTTQILNYEECKEELPESAPIAESNICSSSLQQSKSACN 218
            :  |||      ||..|     .||.|...::..|||::.. :...|.:..:|:...:..|.||.
Human   529 WVTGWG------FSKEKGEIQNILQKVNIPLVTNEECQKRY-QDYKITQRMVCAGYKEGGKDACK 586

  Fly   219 GDSGGPLVVEFTNAPSELIGIVSWGYIPCGLANMPSIYTKVSAYIDWI 266
            ||||||||.:. |....|:||.|||. .|.....|.:||||:.|:|||
Human   587 GDSGGPLVCKH-NGMWRLVGITSWGE-GCARREQPGVYTKVAEYMDWI 632

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11911NP_608518.1 Tryp_SPc 37..269 CDD:238113 78/243 (32%)
Tryp_SPc 37..266 CDD:214473 76/241 (32%)
KLKB1XP_011530232.1 APPLE 21..104 CDD:128519
APPLE 111..194 CDD:128519
APPLE 212..295 CDD:128519
APPLE 303..386 CDD:128519
Tryp_SPc 401..632 CDD:214473 76/241 (32%)
Tryp_SPc 402..632 CDD:238113 76/241 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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