DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG11911 and KLK2

DIOPT Version :9

Sequence 1:NP_608518.1 Gene:CG11911 / 33206 FlyBaseID:FBgn0031249 Length:277 Species:Drosophila melanogaster
Sequence 2:NP_005542.1 Gene:KLK2 / 3817 HGNCID:6363 Length:261 Species:Homo sapiens


Alignment Length:278 Identity:81/278 - (29%)
Similarity:124/278 - (44%) Gaps:33/278 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 VTLVIALVAAAQGAKLSDKLAKLVPSFATGFVINGTEAEPHSAPYIVSLATNYLKHSHICGGTLI 70
            :.|.|||.....||         ||...:. ::.|.|.|.||.|:.|::.::...|   |||.|:
Human     4 LVLSIALSVGCTGA---------VPLIQSR-IVGGWECEKHSQPWQVAVYSHGWAH---CGGVLV 55

  Fly    71 NKDWIVTAAHCISEPVGMSIIAGLHTRAEVDELTQQRQVDFGRVHEKYTGGV-----------GP 124
            :..|::|||||:.:  ...:..|.|...|.::..|:..|.....|..|...:           ..
Human    56 HPQWVLTAAHCLKK--NSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSS 118

  Fly   125 YDIALLHVNESFIFNEWVQPATLPSREQVHEGETHLYGWGQPKSYIFSGAKTLQTVTTQILNYEE 189
            :|:.||.::|.....:.|:...||::|.......:..|||..:...|...::||.|:..:|:.:.
Human   119 HDLMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDM 183

  Fly   190 CKEELPESAPIAESNICSSSLQQSKSACNGDSGGPLVVEFTNAPSELIGIVSWGYIPCGLANMPS 254
            |.....|.  :.|..:|:......|..|.||||||||..     ..|.||.|||..||.|...|:
Human   184 CARAYSEK--VTEFMLCAGLWTGGKDTCGGDSGGPLVCN-----GVLQGITSWGPEPCALPEKPA 241

  Fly   255 IYTKVSAYIDWITNIQSA 272
            :||||..|..||.:..:|
Human   242 VYTKVVHYRKWIKDTIAA 259

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11911NP_608518.1 Tryp_SPc 37..269 CDD:238113 72/242 (30%)
Tryp_SPc 37..266 CDD:214473 70/239 (29%)
KLK2NP_005542.1 Tryp_SPc 25..256 CDD:238113 72/242 (30%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D433637at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

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