DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11911 and TMPRSS7

DIOPT Version :9

Sequence 1:	NP_608518.1	Gene:	CG11911 / 33206	FlyBaseID:	FBgn0031249	Length:	277	Species:	Drosophila melanogaster
Sequence 2:	NP_001382436.1	Gene:	TMPRSS7 / 344805	HGNCID:	30846	Length:	843	Species:	Homo sapiens

Alignment Length:	240	Identity:	70/240 - (29%)
Similarity:	121/240 - (50%)	Gaps:	20/240 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 VINGTEAEPHSAPYIVSLATNYLKHSHICGGTLINKDWIVTAAHC-----ISEPVGMSIIAGLHT 96
            :|.||:......|:.|||   :...|..||.::|:::|:::||||     :|:|...:...|::.
Human   606 IIGGTDTLEGGWPWQVSL---HFVGSAYCGASVISREWLLSAAHCFHGNRLSDPTPWTAHLGMYV 667

  Fly    97 RAEVDELTQQRQVDFGRVHEKYTGGVGPYDIALLHVNESF--IFNEWVQPATL-PSREQVHEGE- 157
            :.....::..|::   .|||.|......||||||.::.::  ...:.:||..: |:.::|..||
Human   668 QGNAKFVSPVRRI---VVHEYYNSQTFDYDIALLQLSIAWPETLKQLIQPICIPPTGQRVRSGEK 729

  Fly   158 THLYGWGQPKSYIFSGAKTLQTVTTQILNYEECKEELPESAPIAESNICSSSLQQSKSACNGDSG 222
            ..:.|||:.......|:..||....::::...|   :.....|....:|:..:...:.||.||||
Human   730 CWVTGWGRRHEADNKGSLVLQQAEVELIDQTLC---VSTYGIITSRMLCAGIMSGKRDACKGDSG 791

  Fly   223 GPLVV-EFTNAPSELIGIVSWGYIPCGLANMPSIYTKVSAYIDWI 266
            |||.. ..::....|.||||||: ..|..|.|.:||:||.::.||
Human   792 GPLSCRRKSDGKWILTGIVSWGH-GSGRPNFPGVYTRVSNFVPWI 835

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11911	NP_608518.1	Tryp_SPc	37..269	CDD:238113	70/240 (29%)
CG11911	NP_608518.1	Tryp_SPc	37..266	CDD:214473	68/238 (29%)
TMPRSS7	NP_001382436.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..67
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010