DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11911 and Prss53

DIOPT Version :9

Sequence 1:	NP_608518.1	Gene:	CG11911 / 33206	FlyBaseID:	FBgn0031249	Length:	277	Species:	Drosophila melanogaster
Sequence 2:	NP_001074737.1	Gene:	Prss53 / 330657	MGIID:	2652890	Length:	552	Species:	Mus musculus

Alignment Length:	230	Identity:	67/230 - (29%)
Similarity:	103/230 - (44%)	Gaps:	33/230 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 LKHSH---ICGGTLINKDWIVTAAHCISEPVGMSII----AGLHTRAEVDELTQQRQVDFGRVHE 116
            ||| |   .|||.|:::..::|||||.   :|...:    .||....|...|.|.      .:|.
Mouse   318 LKH-HGKLACGGALVSEVVVLTAAHCF---IGRQTLEEWSVGLGAGPEEWGLKQL------ILHG 372

  Fly   117 KYTGGVGPYDIALLHVNESFIFNEWVQPATLP-SREQVHEGETHLYGW--GQPKSYIFSGAKTLQ 178
            .||...|.||:|.|.:.:.......::|..|| :...:.:||   :||  |..:.   :|....|
Mouse   373 AYTHPEGGYDVAFLLLAQPVTLGPGLRPLCLPYADHHLPDGE---HGWVLGLTQK---AGINYPQ 431

  Fly   179 TVTTQILNYEECKEE--LP--ESAPIAESNICSSSLQQSKSACNGDSGGPLVVEFTNAPSELIGI 239
            ||...:|....|..:  .|  ...||....:|::.:.:... |.|.||.|||.|. .....|:|:
Mouse   432 TVPVTVLGPMACSRQHAAPGGTGIPILPGMVCTTVVGEPPH-CEGLSGAPLVHEI-RGTWFLVGL 494

  Fly   240 VSWGYIPCGLANMPSIYTKVSAYIDWITNIQSAYY 274
            .|:| ..|..:..|:::..:|||.|||:|:....|
Mouse   495 HSFG-DTCQSSAKPAVFAALSAYEDWISNLDWQVY 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11911	NP_608518.1	Tryp_SPc	37..269	CDD:238113	65/223 (29%)
CG11911	NP_608518.1	Tryp_SPc	37..266	CDD:214473	63/220 (29%)
Prss53	NP_001074737.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..46
		Tryp_SPc	45..271	CDD:238113
		Tryp_SPc	311..522	CDD:238113	65/222 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010