DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11911 and Klkb1

DIOPT Version :9

Sequence 1:	NP_608518.1	Gene:	CG11911 / 33206	FlyBaseID:	FBgn0031249	Length:	277	Species:	Drosophila melanogaster
Sequence 2:	NP_036857.2	Gene:	Klkb1 / 25048	RGDID:	67382	Length:	638	Species:	Rattus norvegicus

Alignment Length:	271	Identity:	91/271 - (33%)
Similarity:	136/271 - (50%)	Gaps:	20/271 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 AQGAK-LSDKLAKLVPSF-----ATGFVINGTEAEPHSAPYIVSLATNYLKHSHICGGTLINKDW 74
            |||:. .|.:|.|:|.|.     ....::.||.:.....|:.|||....:..:|:|||::|.:.|
  Rat   364 AQGSSGYSLRLCKVVESSDCTTKINARIVGGTNSSLGEWPWQVSLQVKLVSQNHMCGGSIIGRQW 428

  Fly    75 IVTAAHC---ISEPVGMSIIAGLHTRAEVDELTQQRQVDFGRVHEKYTGGVGPYDIALLHVNESF 136
            |:|||||   |..|....|..|:...:|:...|....:....:|:||....|.|||||:.:....
  Rat   429 ILTAAHCFDGIPYPDVWRIYGGILNLSEITNKTPFSSIKELIIHQKYKMSEGSYDIALIKLQTPL 493

  Fly   137 IFNEWVQPATLPSREQVHEGETHLY--GWGQPKSYIFSG--AKTLQTVTTQILNYEECKEELPES 197
            .:.|:.:|..|||:...:...|:.:  |||..|.   .|  ...||..|..::..|||:::..:.
  Rat   494 NYTEFQKPICLPSKADTNTIYTNCWVTGWGYTKE---RGETQNILQKATIPLVPNEECQKKYRDY 555

  Fly   198 APIAESNICSSSLQQSKSACNGDSGGPLVVEFTNAPSELIGIVSWGYIPCGLANMPSIYTKVSAY 262
            . |.:..||:...:....||.||||||||.:.:.. .:|:||.|||. .|.....|.:||||:.|
  Rat   556 V-ITKQMICAGYKEGGIDACKGDSGGPLVCKHSGR-WQLVGITSWGE-GCARKEQPGVYTKVAEY 617

  Fly   263 IDWI-TNIQSA 272
            |||| ..|||:
  Rat   618 IDWILEKIQSS 628

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11911	NP_608518.1	Tryp_SPc	37..269	CDD:238113	80/239 (33%)
CG11911	NP_608518.1	Tryp_SPc	37..266	CDD:214473	78/235 (33%)
Klkb1	NP_036857.2	APPLE	21..104	CDD:128519
		APPLE	111..194	CDD:128519
		APPLE	201..284	CDD:128519
		APPLE	292..375	CDD:128519	4/10 (40%)
		Tryp_SPc	390..621	CDD:214473	78/236 (33%)
		Tryp_SPc	391..621	CDD:238113	78/235 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910