Protein Alignment CG11911 and Tmprss13

DIOPT Version :10

• Sequence 1: NP_608518.1
• Gene: CG11911 / 33206
• FlyBaseID: FBgn0031249
• Length: 277
• Species: Drosophila melanogaster
• Sequence 2: XP_006510195.1
• Gene: Tmprss13 / 214531
• MGIID: 2682935
• Length: 561
• Species: Mus musculus
• Alignment Length: 773
• Identity: 146/773 - (18%)
• Similarity: 268/773 - (34%)
• Gaps: 198/773 - (25%)

  Fly   102 KSKKKKKKAKKLKPQ-------AETDSSEDDSGFDDQPKKKNKPEKES-PPVKS-------KKND 151
            :::|||:|.:...||       |.|.||...||........:.|..|. |..||       :..|
Mouse   154 QNQKKKRKVEPPTPQEPGPAKMAVTSSSGGSSGSSSSSSSSSIPSAEKVPTTKSTLWQEEMRAKD 218

  Fly   152 REPGEGAEAATTQKEPEPPKSS----------------------------------SSTKLQQNQ 182
            :..|.......:..:.:||.:.                                  |..|.:|:.
Mouse   219 QPDGTSLSPVQSPSQSQPPAACTPRETGLDSKEDENILSGDRVDGGRKVRVESGYFSLEKAKQDL 283

  Fly   183 SKQNNATKVSDKPVPE-PYSTADYTAWVQLGVSEPIVRALADKGFKVPTEI-----------QNK 235
            ..:.....:...|.|. |:|....       |.|.......:|...:.|.:           |.:
Mouse   284 RAEEQLPPLLSPPSPSTPHSRRSQ-------VIEKFEALDIEKAEHMETNMLILTTPSSDTRQGR 341

  Fly   236 SLPVAIYGRRDLLGAAETGSGKTLAFGIPMLEGIMHLKKGKKPVADDSSEHEMTPPSEDME---V 297
            |...||..:||.  |:||.:. .|:...|:..     .:..|.:...|:|..|||...:.:   :
Mouse   342 SERRAIPRKRDF--ASETPTA-PLSDACPLSP-----HRRAKSLDRRSTESSMTPDLLNFKKGWL 398

  Fly   298 TE--EDAK------VFAEEGRKLGNSSAAPEDKPLYGLILTPT----RELAVQINDHLKAVAKYT 350
            |:  ||.:      |.|::..:....|.|.|...|.|.|...|    .|..||.|...:...|..
Mouse   399 TKQYEDGQWKKHWFVLADQSLRYYRDSVAEEAADLDGEINLSTCYDVTEYPVQRNYGFQIHTKEG 463

  Fly   351 DINIATVFGG-----LATVKQERMLRKCPEIVIATPGRLWELVKSENHHLSKVTDIRYLVIDETD 410
            :..::.:..|     :.|:.:..:....|::..:.|       :.:|...|..|.:|.....|.:
Mouse   464 EFTLSAMTSGIRRNWIQTIMKHVLPTSAPDVTSSLP-------EGKNKSTSFDTCLRPSEKQEAE 521

  Fly   411 ----------------------RMLEKGHFEELKELLALINANEEAKKLRRNYIFSATLTMDHEM 453
                                  :..:...|..:::.|    |.|.|         |...:.|...
Mouse   522 PGEPDPEQKKSRARERRREGRSKTFDWAEFRPIQQAL----AQERA---------STVGSSDSGD 573

  Fly   454 PTHIKRHP--KKSKKALKLTPGQRMANLIET---IGMTDPKI-VDLTQDHGTART--LTESRILC 510
            |..::..|  .:.::|.:....::...:::|   .||.|..: :|:.:..|...|  |....:..
Mouse   574 PGCLEAEPGELERERARRREERRKRFGMLDTNDGPGMEDTALRMDIDRSPGLLGTPDLKTQNVHV 638

  Fly   511 QMEHKDFYLYYFLDRHPGRTLVFCNSIDCVKRLVSLFDYLNCQPLSLFGSMQQRQRLKNLERLTV 575
            ::|.:    ::.::..|.|.          ::.|.:      .||.|  |::.|....:...||.
Mouse   639 EIEQR----WHQVETTPLRE----------EKQVPI------APLHL--SLEDRSERLSTHELTS 681

  Fly   576 LL-----IGPSEVRDYVKLN---QD-----LGR----TEDLPLYPTSERVMRQVKERVTLARQIE 623
            ||     ....|..|.::.|   ||     |||    .|...|..|.||....::|  |..::||
Mouse   682 LLEKELEQSQKEASDLLEQNRLLQDQLRVALGREQSAREGYVLQATCERGFAAMEE--THQKKIE 744

  Fly   624 RMDLQQRRE-GATRSWEDQLAKEFQS------ESEVDSEQEEVRRTEQTKRKRQFRAKRLELSQL 681
            .:..|.:|| ...|..:|:|..|..:      |:..::.:||:.|..:..::.|..:...::..|
Mouse   745 DLQRQHQRELEKLREEKDRLLAEETAATISAIEAMKNAHREEMERELEKSQRSQISSINSDIEAL 809

  Fly   682 LARPIVAERIEMSYPSLNINPTMSEPAATEQSAITVVRKAEQQRILEKKQQRKKKRAN 739
              |....|.::.....|.:..........|.:.:....:||:|.:  ::.||:.:..|
Mouse   810 --RRQYLEELQSVQRELEVLSEQYSQKCLENAHLAQALEAERQAL--RQCQRENQELN 863

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11911	NP_608518.1	Tryp_SPc	37..266	CDD:214473	43/224 (19%)
Tmprss13	XP_006510195.1	PHA03378	<6..>122	CDD:223065
		SRCR_2	225..315	CDD:464747	11/96 (11%)
		Tryp_SPc	319..548	CDD:214473	45/243 (19%)