Protein Alignment CG11911 and Plg

DIOPT Version :10

• Sequence 1: NP_608518.1
• Gene: CG11911 / 33206
• FlyBaseID: FBgn0031249
• Length: 277
• Species: Drosophila melanogaster
• Sequence 2: NP_032903.3
• Gene: Plg / 18815
• MGIID: 97620
• Length: 812
• Species: Mus musculus
• Alignment Length: 669
• Identity: 122/669 - (18%)
• Similarity: 204/669 - (30%)
• Gaps: 216/669 - (32%)

  Fly    74 KKKSKRKRSFDSDSDDSDDDSDDSEKETKSKKKKKKAKKLKPQAETDSSEDDSGFDDQPKKKNKP 138
            |...|||..||:|                   ..|:.:.|:....|.:......:.|.|...: |
Mouse   909 KTPKKRKSIFDAD-------------------VFKRPETLEYVKHTHTHSPQGSWTDTPAPPD-P 953

  Fly   139 EKESPPVKSKKNDREPGEGAEAATTQKEPEPPKSSSST-------------------KLQQNQSK 184
            .|.|...|.|...:.........|....|..|...||:                   :||:.:.|
Mouse   954 PKRSDSFKFKHKTQGSSASDSTVTAGSPPATPVQESSSADADACVLQDGCVNNTDPIELQRGRPK 1018

  Fly   185 -----QNNATKVS---------DKPVPEP-------------YSTA------------------- 203
                 :.|.|.:.         |:..|||             :|:|
Mouse  1019 SAPAPRRNLTPLKMPYTQSFSHDEQSPEPVDLVRFSPFRSNRHSSAFTAGHSLTAPRALSPYPAV 1083

  Fly   204 -------DYTAW---VQLGVSEPIV-------------RALADKGFKVPTEIQNKSLPVAIYGRR 245
                   .||||   |:...|..:.             |...|...|...|:.:.|.....:...
Mouse  1084 TAVMRNPVYTAWSHCVKTTNSASVPSHTYTQVSPQHQGRWSVDLNHKRSAELFDNSRGSGAHNTH 1148

  Fly   246 DLLGAAETGSG--KTLAFGIP----MLEGIMHLKKGKKPVADDSSEHEMTPPSEDMEVTEEDAKV 304
            .|..:|..|..  :.....||    ....:....:|....:|.||...:|||...|    :.|..
Mouse  1149 SLPSSARQGLSQYREQRIKIPSTPRYARSVHGSDRGSLSHSDCSSPSLVTPPLSPM----DSASY 1209

  Fly   305 FAEEGRKLGNS------SAAPEDKPLYGLILTPTRELAVQINDHLKAVAKYTDINIATVFGGLAT 363
            .:.:.:..|::      |..|.|:         .|:..|..|.....:::    :..:.|..|.|
Mouse  1210 TSGQSQASGSTHSRLSVSPVPIDR---------RRDRCVLRNRSFLKLSR----SQRSWFASLRT 1261

  Fly   364 VKQERMLRKCPEIVIATPGRL---WELVKSENH--HLSKVTDIRYLVIDETDRMLEKGHFEELKE 423
            :   |...:.|..|....|..   ..:|..:|.  .:||||:         ..:.:|.|.|...:
Mouse  1262 L---RPFIEEPRYVTIPKGAEPLGISIVGGDNGGIFVSKVTE---------GSIAQKHHLEFGDQ 1314

  Fly   424 LLAL--INANEEAKKLRRNYIFSA--TLTMDHEMPTHIKRHPKKSKKALKL--------TPG--Q 474
            ||..  :|.....::|.|..|...  |:|:..:..||:::....|:.:.::        |||  .
Mouse  1315 LLEFNGVNLRNATEQLARLIIGQQCDTITILAQYNTHMQQLGNHSRSSSRMESSLSSHSTPGTPD 1379

  Fly   475 RMANLIETIGMTDPKIVDLTQDHGTARTLTESRILCQMEHKDFYLYYFLDRHPGRTLVFCNSID- 538
            ..:| |:|:.         .||.||....::........|::       ...|.:.|:....:|
Mouse  1380 THSN-IDTLS---------EQDEGTMTPPSKQATPTSSPHRE-------RAEPRQVLLRKTPVDL 1427

  Fly   539 ----CVKRLVSLFD----------------YLNCQPLSLFGSMQQRQRLKNLERLTVLLIGPSE- 582
                |...|..:|.                .|.|..:|:        :.|..|.:.:.|:.|:|
Mouse  1428 GMRICGGNLTGVFVEDLEDGGAHGLQPGDLILECNSVSM--------KSKTAEEVYLELLKPAEN 1484

  Fly   583 -VRDYVKLNQDLGRTEDLP 600
             |.......|...|.:|.|
Mouse  1485 IVLRVQNRPQHFRRAKDTP 1503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11911	NP_608518.1	Tryp_SPc	37..266	CDD:214473	49/285 (17%)
Plg	NP_032903.3	PAN_AP_HGF	<38..97	CDD:238532
		KR	101..183	CDD:214527
		KR	183..262	CDD:214527
		KR	273..354	CDD:214527
		KR	375..456	CDD:214527
		KR	480..562	CDD:214527
		Tryp_SPc	582..807	CDD:238113