Protein Alignment CG11911 and CFD

DIOPT Version :10

• Sequence 1: NP_608518.1
• Gene: CG11911 / 33206
• FlyBaseID: FBgn0031249
• Length: 277
• Species: Drosophila melanogaster
• Sequence 2: NP_001304264.1
• Gene: CFD / 1675
• HGNCID: 2771
• Length: 260
• Species: Homo sapiens
• Alignment Length: 279
• Identity: 79/279 - (28%)
• Similarity: 127/279 - (45%)
• Gaps: 42/279 - (15%)

  Fly     6 VTLVIALVAAAQGAKLSDKLAKLVPSFATGFVINGTEAEPHSAPYIVSLATNYLKHSHICGGTLI 70
            :.:::.|.|||.|   .:..|...|  ..|.::.|.|||.|:.||:.|:..|   .:|:|||.|:
Human     7 LAVLVLLGAAACG---EEAWAWAAP--PRGRILGGREAEAHARPYMASVQLN---GAHLCGGVLV 63

  Fly    71 NKDWIVTAAHCISEPVG--MSIIAGLHTRAEVDELTQQRQVDFGRV--HEKYTGGVGPYDIALLH 131
            .:.|:::||||:.:...  :.::.|.|:.::.:  ..:|..|..|.  |.........:|:.||.
Human    64 AEQWVLSAAHCLEDAADGKVQVLLGAHSLSQPE--PSKRLYDVLRAVPHPDSQPDTIDHDLLLLQ 126

  Fly   132 VNESFIFNEWVQPATLP----SREQVHEGETHLYGWG-------QPKSYIFSGAKTLQTVTTQIL 185
            ::|.......|:|  ||    .|:........:.|||       :|.|        ||.|...:|
Human   127 LSEKATLGPAVRP--LPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDS--------LQHVLLPVL 181

  Fly   186 NYEECKEELPESAPIAESNICSSSLQQSKSACNGDSGGPLVVEFTNAPSELIGIVSWGYIPCGLA 250
            :...|.........|.|..:|:.|  ..:.:|.||||||||     ....|.|:|:.|...||..
Human   182 DRATCNRRTHHDGAITERLMCAES--NRRDSCKGDSGGPLV-----CGGVLEGVVTSGSRVCGNR 239

  Fly   251 NMPSIYTKVSAYIDWITNI 269
            ..|.|||:|::|..||.::
Human   240 KKPGIYTRVASYAAWIDSV 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11911	NP_608518.1	Tryp_SPc	37..266	CDD:214473	69/243 (28%)
CFD	NP_001304264.1	Tryp_SPc	33..258	CDD:238113	71/246 (29%)