Protein Alignment CG11911 and PRSS21

DIOPT Version :10

• Sequence 1: NP_608518.1
• Gene: CG11911 / 33206
• FlyBaseID: FBgn0031249
• Length: 277
• Species: Drosophila melanogaster
• Sequence 2: NP_006790.1
• Gene: PRSS21 / 10942
• HGNCID: 9485
• Length: 314
• Species: Homo sapiens
• Alignment Length: 298
• Identity: 89/298 - (29%)
• Similarity: 128/298 - (42%)
• Gaps: 52/298 - (17%)

  Fly     8 LVIALVAAAQG---------AKLSDKLAKLVPSFATGFVINGTEAEPHSAPYIVSLATNYLKHSH 63
            |::||:.|..|         |.||....:.|   .|..::.|.:||....|:..||.   |..||
Human     7 LLLALLLARAGLRKPESQEAAPLSGPCGRRV---ITSRIVGGEDAELGRWPWQGSLR---LWDSH 65

  Fly    64 ICGGTLINKDWIVTAAHC------ISEPVGMSIIAGLHTRAEVDELTQQRQVDFGRVHEKYTG-- 120
            :||.:|::..|.:|||||      :|:|.|..:..|        :||.  ...|..:...||.
Human    66 VCGVSLLSHRWALTAAHCFETYSDLSDPSGWMVQFG--------QLTS--MPSFWSLQAYYTRYF 120

  Fly   121 -----------GVGPYDIALLHVNESFIFNEWVQPATLPSREQVHEGETHLY--GWGQPK-SYIF 171
                       |..||||||:.::....:.:.:||..|.:.....|..|..:  |||..| ....
Human   121 VSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEAL 185

  Fly   172 SGAKTLQTVTTQILNYEECKE---ELPESAPIAESNICSSSLQQSKSACNGDSGGPLVVEFTNAP 233
            ....|||.|...|:|...|..   :......|....:|:.:.|..|.||.|||||||... .|..
Human   186 PSPHTLQEVQVAIINNSMCNHLFLKYSFRKDIFGDMVCAGNAQGGKDACFGDSGGPLACN-KNGL 249

  Fly   234 SELIGIVSWGYIPCGLANMPSIYTKVSAYIDWITNIQS 271
            ...||:|||| :.||..|.|.:||.:|.:.:||..:.:
Human   250 WYQIGVVSWG-VGCGRPNRPGVYTNISHHFEWIQKLMA 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11911	NP_608518.1	Tryp_SPc	37..266	CDD:214473	77/253 (30%)
PRSS21	NP_006790.1	Tryp_SPc	42..283	CDD:238113	79/255 (31%)