DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11912 and tmprss7

DIOPT Version :9

Sequence 1:	NP_608517.1	Gene:	CG11912 / 33205	FlyBaseID:	FBgn0031248	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	XP_002666699.2	Gene:	tmprss7 / 798480	ZFINID:	ZDB-GENE-130530-883	Length:	840	Species:	Danio rerio

Alignment Length:	267	Identity:	84/267 - (31%)
Similarity:	123/267 - (46%)	Gaps:	50/267 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 PEGRIINGYEAAKGEAPYIVSLQTTSNSHFCAGSLLDEVTIVTAAHCLT---------------- 74
            |:.||:.|..|.:||.|:.||:. .|...:|..|:|.:|.:::||||.:
Zfish   598 PQQRIVGGVNAVEGEWPWQVSMH-FSGQLYCGASVLSDVWLISAAHCYSKERLADPRMWMAHLGM 661

  Fly    75 YNQGQAVAGAHSRTDQENVQIRKFTNAQYVIHENYGGGVGPNDIGLILLKEEDAFDLNAVARDGS 139
            .|||.|         :...:||:.     |:||.|.......||.|:.||:.....|....:
Zfish   662 LNQGSA---------KHVAEIRRI-----VVHEYYNARNFDYDIALLQLKKVWPSGLEQYIQ--- 709

  Fly   140 NPVSAVSLPSKTFQGTSDGYLYGWG--RDNSGLLPLNLQKLDAIIVDYNECKAALPSNNSLAETN 202
             || .:..||:||......::.|||  .:...:||..|||.:..::..:|||.   |...::...
Zfish   710 -PV-CLPAPSQTFTEGHRCWVTGWGYRSEQDKVLPTVLQKAEVNVLSQSECKR---SYGPVSPRM 769

  Fly   203 VCTHTPGKADGSCNGDSGGPLVSQSSSRGAE--LIGIVSWGYTPCLSTTYPSVYTSVSSFLPWI- 264
            :|...|.....:|.|||||||..|:.: |:.  |.|||||| :.|.....|.|||.|:.|:.||
Zfish   770 LCAGVPSGEQDACRGDSGGPLSCQAQT-GSRWFLTGIVSWG-SGCGRPYLPGVYTRVAKFIDWIQ 832

  Fly   265 ----DEN 267
                |||
Zfish   833 RHIHDEN 839

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11912	NP_608517.1	Tryp_SPc	29..264	CDD:214473	78/254 (31%)
CG11912	NP_608517.1	Tryp_SPc	30..267	CDD:238113	80/261 (31%)
tmprss7	XP_002666699.2	SEA	99..203	CDD:307516
		CUB	<260..344	CDD:238001
		CUB	367..465	CDD:294042
		LDLa	472..506	CDD:238060
		LDLa	546..581	CDD:238060
		Tryp_SPc	601..831	CDD:214473	78/254 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010