DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11912 and Prss36

DIOPT Version :9

Sequence 1:	NP_608517.1	Gene:	CG11912 / 33205	FlyBaseID:	FBgn0031248	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	XP_017167884.1	Gene:	Prss36 / 77613	MGIID:	1924863	Length:	863	Species:	Mus musculus

Alignment Length:	282	Identity:	82/282 - (29%)
Similarity:	122/282 - (43%)	Gaps:	46/282 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 SAISVPQPGF---------PEGRIINGYEAAKGEAPYIVSLQTTSNSHFCAGSLLDEVTIVTAAH 71
            |.:|..|..|         |..||:.|.:|..|..|:.|||. ....|.|.|||:....:::|||
Mouse    25 SVVSPTQGEFEDLDCGRPEPSSRIVGGSDAHPGTWPWQVSLH-QGGGHICGGSLIAPSWVLSAAH 88

  Fly    72 CLTYN-------QGQAVAGAHSRTDQ-ENVQIRKFTNAQYVIHENYGGGVGPNDIG--LILLKEE 126
            |...|       :...:.|.||:... |...:|..  |..:|.:||    ...::|  |.||:
Mouse    89 CFVTNGTLEPADELSVLLGVHSQDGPLEGAHMRSV--ATILIPDNY----STVELGADLALLR-- 145

  Fly   127 DAFDLNAVARDGSNPVSAVSLP--SKTFQGTSDGYLYGWGRDNSGL---LPLNLQKLDAIIVDYN 186
                |.:.|:.|.: |..|.||  |..|...:..:..|||.....:   ||..||:::..::...
Mouse   146 ----LASPAKLGPS-VRPVCLPRASHLFAHGTACWATGWGDVQEAVPLPLPWVLQEVELRLLGEA 205

  Fly   187 ECKAAL----PSNNS--LAETNVCTHTPGKADGSCNGDSGGPLVSQSSSRGAELIGIVSWGYTPC 245
            .|:...    |.|.:  |....:|...|.....:|.||||||||.:...|.. |.||.|:|: .|
Mouse   206 ACQCLYSRPGPFNLTFQLLPGMLCAGYPAGRRDTCQGDSGGPLVCEDGGRWF-LAGITSFGF-GC 268

  Fly   246 LSTTYPSVYTSVSSFLPWIDEN 267
            .....|.|:|:|:.:..||.|:
Mouse   269 GRRNRPGVFTAVAPYESWIREH 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11912	NP_608517.1	Tryp_SPc	29..264	CDD:214473	74/255 (29%)
CG11912	NP_608517.1	Tryp_SPc	30..267	CDD:238113	75/257 (29%)
Prss36	XP_017167884.1	Tryp_SPc	48..290	CDD:238113	75/257 (29%)
		Tryp_SPc	331..532	CDD:389826
		Tryp_SPc	607..789	CDD:389826
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010