Protein Alignment CG11912 and TPSB2

DIOPT Version :10

• Sequence 1: NP_608517.1
• Gene: CG11912 / 33205
• FlyBaseID: FBgn0031248
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: NP_077078.5
• Gene: TPSB2 / 64499
• HGNCID: 14120
• Length: 275
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 83/282 - (29%)
• Similarity: 131/282 - (46%)
• Gaps: 42/282 - (14%)

  Fly     6 VIFALALASVSAISVPQPGFPEGR--IINGYEAAKGEAPYIVSLQTTSN--SHFCAGSLLDEVTI 66
            ::.||.:.:..|.:.|.||....|  |:.|.||.:.:.|:.|||:....  .|||.|||:....:
Human     5 LLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWV 69

  Fly    67 VTAAHCLTYN-QGQAVAGAHSRTDQENVQIRKFTNAQYVIH-ENYGGGVGPNDIGLILLKEEDAF 129
            :|||||:..: :..|......|......|.:....::.::| :.|...:|. ||.|:.|:|
Human    70 LTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGA-DIALLELEE---- 129

  Fly   130 DLNAVARDGSNPVSAVSLP--SKTFQGTSDGYLYGWGR-DNSGLL--PLNLQKLDAIIVDYNECK 189
            .:|.     |:.|..|:||  |:||......::.|||. ||...|  |..|:::...|::.:.|.
Human   130 PVNV-----SSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICD 189

  Fly   190 A------------ALPSNNSLAETNVCTHTPGKADGSCNGDSGGPLVSQSSSRGAELIGIVSWGY 242
            |            .:..::.|...|.      :.| ||.||||||||.:.:....: .|:||||
Human   190 AKYHLGAYTGDDVRIVRDDMLCAGNT------RRD-SCQGDSGGPLVCKVNGTWLQ-AGVVSWG- 245

  Fly   243 TPCLSTTYPSVYTSVSSFLPWI 264
            ..|.....|.:||.|:.:|.||
Human   246 EGCAQPNRPGIYTRVTYYLDWI 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11912	NP_608517.1	Tryp_SPc	29..264	CDD:214473	75/257 (29%)
TPSB2	NP_077078.5	Tryp_SPc	31..268	CDD:238113	76/256 (30%)