DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11912 and tmprss5

DIOPT Version :9

Sequence 1:	NP_608517.1	Gene:	CG11912 / 33205	FlyBaseID:	FBgn0031248	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	XP_009289870.1	Gene:	tmprss5 / 569688	ZFINID:	ZDB-GENE-131121-184	Length:	551	Species:	Danio rerio

Alignment Length:	247	Identity:	82/247 - (33%)
Similarity:	121/247 - (48%)	Gaps:	24/247 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 RIINGYEAAKGEAPYIVSLQTTSNSHFCAGSLLDEVTIVTAAHCL-TYNQGQ-----AVAGAHSR 87
            |||.|.|||.|..|:.|||. .:|.|.|.||::....|||||||: .|...|     ..||..:.
Zfish   311 RIIGGVEAALGRWPWQVSLY-YNNRHICGGSIITNQWIVTAAHCVHNYRLPQVPSWVVYAGIITS 374

  Fly    88 TDQENVQIRKFTNAQYVIHENYGGGVGPNDIGLILLKEEDAFDLNAVARDGSNPVSAVSLP--SK 150
            ...:..|.:.|...:.:.::||......|||.|:.||....|         |:.:..|.||  ..
Zfish   375 NLAKLAQYQGFAVERIIYNKNYNHRTHDNDIALVKLKTPLNF---------SDTIRPVCLPQYDH 430

  Fly   151 TFQGTSDGYLYGWG--RDNSGLLPLNLQKLDAIIVDYNECKAALPSNNSLAETNVCT-HTPGKAD 212
            ...|.:..::.|||  :.:..|:|..|::....::...:|.::...|..:....:|. ::.||.|
Zfish   431 DLPGGTQCWISGWGYTQPDDVLIPEVLKEAPVPLISTKKCNSSCMYNGEITSRMLCAGYSEGKVD 495

  Fly   213 GSCNGDSGGPLVSQSSSRGAELIGIVSWGYTPCLSTTYPSVYTSVSSFLPWI 264
             :|.||||||||.|..:.. .|:|:|||| |.|....:|.||:.|:.||.||
Zfish   496 -ACQGDSGGPLVCQDENVW-RLVGVVSWG-TGCAEPNHPGVYSKVAEFLGWI 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11912	NP_608517.1	Tryp_SPc	29..264	CDD:214473	80/245 (33%)
CG11912	NP_608517.1	Tryp_SPc	30..267	CDD:238113	81/246 (33%)
tmprss5	XP_009289870.1	SRCR_2	211..306	CDD:292133
		Tryp_SPc	311..544	CDD:214473	80/245 (33%)
		Tryp_SPc	312..547	CDD:238113	81/246 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920