Protein Alignment CG11912 and PRSS8

DIOPT Version :10

• Sequence 1: NP_608517.1
• Gene: CG11912 / 33205
• FlyBaseID: FBgn0031248
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: NP_002764.1
• Gene: PRSS8 / 5652
• HGNCID: 9491
• Length: 343
• Species: Homo sapiens
• Alignment Length: 259
• Identity: 80/259 - (30%)
• Similarity: 111/259 - (42%)
• Gaps: 38/259 - (14%)

  Fly    26 PEGRIINGYEAAKGEAPYIVSLQTTSNSHFCAGSLLDEVTIVTAAHCLT---YNQGQAV-AGAHS 86
            |:.||..|..|..|:.|:.||: |....|.|.|||:.|..:::||||..   :.:...| .|||
Human    41 PQARITGGSSAVAGQWPWQVSI-TYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAH- 103

  Fly    87 RTDQENVQIRKFTNAQYVIHENYGGGVGPNDIGLILLKEEDAFDLNAVARDGSNPVSAVSLP--S 149
            :.|..:...:..|....:.|.:|.......||.|:.|.....|         |..:..:.||  :
Human   104 QLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITF---------SRYIRPICLPAAN 159

  Fly   150 KTFQGTSDGYLYGWGR---DNSGLLPLNLQKLDAIIVDYNECKA-----ALPSN-NSLAETNVCT 205
            .:|.......:.|||.   ..|.|.|..||:|:..::....|..     |.|.. :.:.|..||.
Human   160 ASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCA 224

  Fly   206 -HTPGKADGSCNGDSGGPLVSQSSSRGAE----LIGIVSWGYTPCLSTTYPSVYTSVSSFLPWI 264
             :..|..| :|.|||||||     |...|    |.|||||| ..|.:...|.|||..||:..||
Human   225 GYVEGGKD-ACQGDSGGPL-----SCPVEGLWYLTGIVSWG-DACGARNRPGVYTLASSYASWI 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11912	NP_608517.1	Tryp_SPc	29..264	CDD:214473	77/254 (30%)
PRSS8	NP_002764.1	Tryp_SPc	45..284	CDD:238113	78/255 (31%)