DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG11912 and KLK7

DIOPT Version :9

Sequence 1:NP_608517.1 Gene:CG11912 / 33205 FlyBaseID:FBgn0031248 Length:271 Species:Drosophila melanogaster
Sequence 2:NP_005037.1 Gene:KLK7 / 5650 HGNCID:6368 Length:253 Species:Homo sapiens


Alignment Length:265 Identity:83/265 - (31%)
Similarity:125/265 - (47%) Gaps:27/265 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 IFALALASVSAISVPQPGFPEGRIINGYEAAKGEAPYIVSLQTTSNSHFCAGSLLDEVTIVTAAH 71
            |..|:||..:|....|    ..:||:|...|:|..|:.|:|.:.:..| |.|.|::|..::||||
Human    11 ILLLSLALETAGEEAQ----GDKIIDGAPCARGSHPWQVALLSGNQLH-CGGVLVNERWVLTAAH 70

  Fly    72 CLTYNQGQAVAGAHSRTDQENVQIRKFTNAQYVIHENYGGGVGPNDIGLILLKEEDAFDLNAVAR 136
            | ..|:.....|:.:..|:...:|:...:.:   |..|......||  |:|:|      ||:.||
Human    71 C-KMNEYTVHLGSDTLGDRRAQRIKASKSFR---HPGYSTQTHVND--LMLVK------LNSQAR 123

  Fly   137 DGSNPVSAVSLPSKTFQGTSDGYLYGWGRDNSG--LLPLNLQKLDAIIVDYNECKAALPSNNSLA 199
             .|:.|..|.|||:.....:...:.|||...|.  ..|.:|..:|..::...:|....  .:.|.
Human   124 -LSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY--KDLLE 185

  Fly   200 ETNVCTHTPGKADGSCNGDSGGPLVSQSSSRGAELIGIVSWGYTPCLSTTYPSVYTSVSSFLPWI 264
            .:.:|...|.....:||||||||||.:.:     |.|:||||..||.....|.|||.|..|..||
Human   186 NSMLCAGIPDSKKNACNGDSGGPLVCRGT-----LQGLVSWGTFPCGQPNDPGVYTQVCKFTKWI 245

  Fly   265 DENRK 269
            ::..|
Human   246 NDTMK 250

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11912NP_608517.1 Tryp_SPc 29..264 CDD:214473 74/236 (31%)
Tryp_SPc 30..267 CDD:238113 76/238 (32%)
KLK7NP_005037.1 Tryp_SPc 29..245 CDD:214473 74/236 (31%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D433637at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

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