Protein Alignment CG11912 and PRSS1

DIOPT Version :10

• Sequence 1: NP_608517.1
• Gene: CG11912 / 33205
• FlyBaseID: FBgn0031248
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: NP_002760.1
• Gene: PRSS1 / 5644
• HGNCID: 9475
• Length: 247
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 86/265 - (32%)
• Similarity: 123/265 - (46%)
• Gaps: 39/265 - (14%)

  Fly    10 LALASVSAISVPQPGFPEGRIINGYEAAKGEAPYIVSLQTTSNSHFCAGSLLDEVTIVTAAHCLT 74
            |.:.:..|.::..|...:.:|:.||...:...||.|||  .|..|||.|||::|..:|:|.||
Human     4 LLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSL--NSGYHFCGGSLINEQWVVSAGHC-- 64

  Fly    75 YNQGQAVAGAHSRTDQENVQI----RKFTNAQYVI-HENYGGGVGPNDIGLILLKEEDAFDLNAV 134
            |.....|     |..:.|:::    .:|.||..:| |..|......|||.||.|.....  :||
Human    65 YKSRIQV-----RLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAV--INA- 121

  Fly   135 ARDGSNPVSAVSLPSKTFQGTSDGYLYGWGRD-NSGL-LPLNLQKLDAIIVDYNECKAALPSNNS 197
                  .||.:|||:......:...:.|||.. :||. .|..||.|||.::...:|:|:.|  ..
Human   122 ------RVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYP--GK 178

  Fly   198 LAETNVCTHTPGKADG---SCNGDSGGPLVSQSSSRGAELIGIVSWGYTPCLSTTYPSVYTSVSS 259
            :.....|.   |..:|   ||.||||||:|.     ..:|.|:|||| ..|.....|.|||.|.:
Human   179 ITSNMFCV---GFLEGGKDSCQGDSGGPVVC-----NGQLQGVVSWG-DGCAQKNKPGVYTKVYN 234

  Fly   260 FLPWI 264
            ::.||
Human   235 YVKWI 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11912	NP_608517.1	Tryp_SPc	29..264	CDD:214473	81/244 (33%)
PRSS1	NP_002760.1	Tryp_SPc	23..239	CDD:214473	81/244 (33%)