Protein Alignment CG11912 and KLK15

DIOPT Version :10

• Sequence 1: NP_608517.1
• Gene: CG11912 / 33205
• FlyBaseID: FBgn0031248
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: NP_059979.2
• Gene: KLK15 / 55554
• HGNCID: 20453
• Length: 256
• Species: Homo sapiens
• Alignment Length: 277
• Identity: 85/277 - (30%)
• Similarity: 119/277 - (42%)
• Gaps: 44/277 - (15%)

  Fly    10 LALASVSAISVPQPGFPEGRIINGYEAAKGEAPYIVSLQTTSNSHFCAGSLLDEVTIVTAAHCLT 74
            |.|:.:.|.:..|.|   .:::.|.|.|....|:.|:|......: |..||:....:::||||
Human     5 LTLSFLLASTAAQDG---DKLLEGDECAPHSQPWQVALYERGRFN-CGASLISPHWVLSAAHC-- 63

  Fly    75 YNQGQAV---AGAHSRTDQEN-VQIRKFTNAQYVIHENYGGGVGPNDIGLILLKEEDAFDLNAVA 135
              |.:.:   .|.|:...::. .|:|  |.::.:.|..|......|||.|:.|.:.        |
Human    64 --QSRFMRVRLGEHNLRKRDGPEQLR--TTSRVIPHPRYEARSHRNDIMLLRLVQP--------A 116

  Fly   136 RDGSNP-VSAVSLPSKTFQGTSDGYLYGWG---RDNSGL---------LPLNLQKLDAIIVDYNE 187
            |  .|| |....||::.........:.|||   .:..|.         ||..|...:..|:....
Human   117 R--LNPQVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTS 179

  Fly   188 CKAALPSNNSLAETNVCTHTPGKADGSCNGDSGGPLVSQSSSRGAELIGIVSWGYTPCLSTTYPS 252
            |..:.|..  |..|.||....|:...||.||||||||.     |..|.||||||..||.:||.|.
Human   180 CDKSYPGR--LTNTMVCAGAEGRGAESCEGDSGGPLVC-----GGILQGIVSWGDVPCDNTTKPG 237

  Fly   253 VYTSVSSFLPWIDENRK 269
            |||.|..:|.||.|..|
Human   238 VYTKVCHYLEWIRETMK 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11912	NP_608517.1	Tryp_SPc	29..264	CDD:214473	76/251 (30%)
KLK15	NP_059979.2	Tryp_SPc	25..249	CDD:214473	76/247 (31%)