DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11912 and Prss53

DIOPT Version :9

Sequence 1:	NP_608517.1	Gene:	CG11912 / 33205	FlyBaseID:	FBgn0031248	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	XP_006230384.1	Gene:	Prss53 / 499270	RGDID:	1566127	Length:	591	Species:	Rattus norvegicus

Alignment Length:	301	Identity:	61/301 - (20%)
Similarity:	109/301 - (36%)	Gaps:	85/301 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 PGFPEGRIINGYEAAKGEAPYIVSLQTTSNSHFCAGSLLDEVTIVTAAHCLTYNQGQAVAGAHSR 87
            ||.||.:..|   ...||.|:..|:: ....|.|:|||:.:..::|||||.
  Rat    33 PGPPEPQEGN---TLPGEWPWQASVR-RQGVHICSGSLVADTWVLTAAHCF-------------- 79

  Fly    88 TDQENVQIRKFTNAQYVIHENYGGGVGP--NDIGLILLKEEDAFDLNAVARD-----GSNPV--S 143
               |.:...:.::...|:......|:.|  .::|:..|:...|::..:...|     .::|:  :
  Rat    80 ---EKMATAELSSWSVVLGSLKQEGLSPGAEEVGVAALQLPKAYNHYSQGSDLALLQLTHPIVHT 141

  Fly   144 AVSLPSKTF--------------QGTSDGYLYGWGRD----------------------NSGLLP 172
            .:.||..|.              |.||||......:.                      :|.|.|
  Rat   142 TLCLPQPTHHFPFGASCWATGWDQNTSDGKYCPRHKSRESQTGSVLTVLALCSHCVSELDSTLSP 206

  Fly   173 L----NLQKLDAIIVDYNECKA----------ALPSNNSLAETNVCTHTPGKADGSCNGDSGGPL 223
            |    .|:.|...::....|..          |.|:.:.:    :|........|.|.||||||:
  Rat   207 LPVSRTLRNLRLRLISRPTCNCLYNRLHQRLLANPARSGM----LCGGAQPGVQGPCQGDSGGPV 267

  Fly   224 VSQSSSRGAELIGIVSWGYTPCLSTTYPSVYTSVSSFLPWI 264
            :.:........:||:|: .:.|.....|.:.|.:::...|:
  Rat   268 MCREPDGHWVQVGIISF-TSNCAQEDTPVLLTDMAAHSSWL 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11912	NP_608517.1	Tryp_SPc	29..264	CDD:214473	56/293 (19%)
CG11912	NP_608517.1	Tryp_SPc	30..267	CDD:238113	57/294 (19%)
Prss53	XP_006230384.1	Tryp_SPc	45..310	CDD:238113	56/286 (20%)
Prss53	XP_006230384.1	Tryp_SPc	341..561	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010