DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG11912 and KLK14

DIOPT Version :9

Sequence 1:NP_608517.1 Gene:CG11912 / 33205 FlyBaseID:FBgn0031248 Length:271 Species:Drosophila melanogaster
Sequence 2:NP_001298111.2 Gene:KLK14 / 43847 HGNCID:6362 Length:251 Species:Homo sapiens


Alignment Length:287 Identity:88/287 - (30%)
Similarity:127/287 - (44%) Gaps:56/287 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 FAVIFALALASVSAISVPQPGFPEGRIINGYEAAKGEAPYIVSLQTTSNSHF-CAGSLLDEVTIV 67
            |.::.||   .|.||::.|....|.:||.|:...:...|:..:|.......| |.|:||....::
Human     2 FLLLTAL---QVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVI 63

  Fly    68 TAAHCLTYNQG----QAVAGAHSRTDQENVQIRKFTNAQYVI-------HENYGGGVGPNDIGLI 121
            |||||     |    |...|.|:        :|::...|.|:       |.||......||:.|:
Human    64 TAAHC-----GRPILQVALGKHN--------LRRWEATQQVLRVVRQVTHPNYNSRTHDNDLMLL 115

  Fly   122 LLKEEDAFDLNAVARDGS--NPV---SAVSLPSKTFQGTSDGYLYGWGRDNSGL--LPLNLQKLD 179
            .|::.        ||.|.  .|:   .|.:.|     ||| ..:.|||..:|.:  .|.:||.::
Human   116 QLQQP--------ARIGRAVRPIEVTQACASP-----GTS-CRVSGWGTISSPIARYPASLQCVN 166

  Fly   180 AIIVDYNECKAALPSNNSLAETNVCTHTPGKADGSCNGDSGGPLVSQSSSRGAELIGIVSWGYTP 244
            ..|.....|:.|.|  .::....||...|.....||.||||||||    .|| :|.|:||||...
Human   167 INISPDEVCQKAYP--RTITPGMVCAGVPQGGKDSCQGDSGGPLV----CRG-QLQGLVSWGMER 224

  Fly   245 CLSTTYPSVYTSVSSFLPWIDENRKAK 271
            |....||.|||::..:..||:|..:.|
Human   225 CALPGYPGVYTNLCKYRSWIEETMRDK 251

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11912NP_608517.1 Tryp_SPc 29..264 CDD:214473 76/253 (30%)
Tryp_SPc 30..267 CDD:238113 78/255 (31%)
KLK14NP_001298111.2 Tryp_SPc 25..247 CDD:238113 78/255 (31%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D433637at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

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