DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG11912 and TMPRSS11F

DIOPT Version :10

Sequence 1:NP_608517.1 Gene:CG11912 / 33205 FlyBaseID:FBgn0031248 Length:271 Species:Drosophila melanogaster
Sequence 2:NP_997290.2 Gene:TMPRSS11F / 389208 HGNCID:29994 Length:438 Species:Homo sapiens


Alignment Length:265 Identity:85/265 - (32%)
Similarity:111/265 - (41%) Gaps:66/265 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    29 RIINGYEAA-KGEAPYIVSLQTTSNSHFCAGSLLDEVTIVTAAHCLTYN----QGQAVAGAHSRT 88
            ||:.|.|.| :||.|:..|||...:.|.|..||:....::|||||...|    |..|..||....
Human   205 RIVQGRETAMEGEWPWQASLQLIGSGHQCGASLISNTWLLTAAHCFWKNKDPTQWIATFGATITP 269

  Fly    89 DQENVQIRKFTNAQYVIHENYGGGVGPNDIGLILLKEEDAFDLNAVARDGSNPVSAVSLPSKTFQ 153
            ......:||.     ::||||......|||.|:.|.....|. |.|.| ...|.|::.||.||  
Human   270 PAVKRNVRKI-----ILHENYHRETNENDIALVQLSTGVEFS-NIVQR-VCLPDSSIKLPPKT-- 325

  Fly   154 GTSDGYLYGWGRDNSGLLPLNLQKLDAIIVDYNECKAALPSNNSLAE-------TNVCTH----- 206
               ..::.|:|.                |||..      |..|:|.:       |:||..     
Human   326 ---SVFVTGFGS----------------IVDDG------PIQNTLRQARVETISTDVCNRKDVYD 365

  Fly   207 ---TP---------GKADGSCNGDSGGPLVSQSSSRGAELIGIVSWGYTPCLSTTYPSVYTSVSS 259
               ||         ||.| :|.||||||||..:.... .::||||||.: |.....|.|||.|:.
Human   366 GLITPGMLCAGFMEGKID-ACKGDSGGPLVYDNHDIW-YIVGIVSWGQS-CALPKKPGVYTRVTK 427

  Fly   260 FLPWI 264
            :..||
Human   428 YRDWI 432

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11912NP_608517.1 Tryp_SPc 29..264 CDD:214473 83/263 (32%)
TMPRSS11FNP_997290.2 SEA 59..158 CDD:460188
Tryp_SPc 206..435 CDD:238113 84/264 (32%)
Blue background indicates that the domain is not in the aligned region.

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