Protein Alignment CG11912 and KLK2

DIOPT Version :9

• Sequence 1: NP_608517.1
• Gene: CG11912 / 33205
• FlyBaseID: FBgn0031248
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: NP_005542.1
• Gene: KLK2 / 3817
• HGNCID: 6363
• Length: 261
• Species: Homo sapiens
• Alignment Length: 284
• Identity: 79/284 - (27%)
• Similarity: 123/284 - (43%)
• Gaps: 47/284 - (16%)

  Fly     1 MKQFAVIFALALASVSAISVPQPGFPEGRIINGYEAAKGEAPYIVSLQTTSNSHFCAGSLLDEVT 65
            |....:..||::....|:.:.|     .||:.|:|..|...|:.|::.:...:| |.|.|:....
Human     1 MWDLVLSIALSVGCTGAVPLIQ-----SRIVGGWECEKHSQPWQVAVYSHGWAH-CGGVLVHPQW 59

  Fly    66 IVTAAHCLTYNQGQAVAGAHSRTDQENVQIRKFTNAQYVIHENYGGGVGPNDI-GLILLK----- 124
            ::||||||..| .|...|.|:..:.|:      |..:..:..::     |:.: .:.|||
Human    60 VLTAAHCLKKN-SQVWLGRHNLFEPED------TGQRVPVSHSF-----PHPLYNMSLLKHQSLR 112

  Fly   125 --EEDAFDLNAVARDGSNP------VSAVSLPSKTFQGTSDGYLYGWG--RDNSGLLPLNLQKLD 179
              |:.:.||..:..  |.|      |..:.||::.....:..|..|||  .....|.|.:||.:.
Human   113 PDEDSSHDLMLLRL--SEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVS 175

  Fly   180 AIIVDYNECKAALPSNNSLAETNVCT--HTPGKADGSCNGDSGGPLVSQSSSRGAELIGIVSWGY 242
            ..::..:.|..|.  :..:.|..:|.  .|.||  .:|.||||||||.     ...|.||.|||.
Human   176 LHLLSNDMCARAY--SEKVTEFMLCAGLWTGGK--DTCGGDSGGPLVC-----NGVLQGITSWGP 231

  Fly   243 TPCLSTTYPSVYTSVSSFLPWIDE 266
            .||.....|:|||.|..:..||.:
Human   232 EPCALPEKPAVYTKVVHYRKWIKD 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11912	NP_608517.1	Tryp_SPc	29..264	CDD:214473	72/252 (29%)
		Tryp_SPc	30..267	CDD:238113	73/255 (29%)
KLK2	NP_005542.1	Tryp_SPc	25..256	CDD:238113	73/255 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920