Protein Alignment CG11912 and KLK1

DIOPT Version :10

• Sequence 1: NP_608517.1
• Gene: CG11912 / 33205
• FlyBaseID: FBgn0031248
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: NP_002248.1
• Gene: KLK1 / 3816
• HGNCID: 6357
• Length: 262
• Species: Homo sapiens
• Alignment Length: 285
• Identity: 85/285 - (29%)
• Similarity: 129/285 - (45%)
• Gaps: 53/285 - (18%)

  Fly     4 FAVI-FALALASVSAISVPQPGFPEGRIINGYEAAKGEAPYIVSLQTTSNSHF----CAGSLLDE 63
            |.|: .||:|....|....|     .||:.|:|..:...|:..:|.     ||    |.|.|:..
Human     3 FLVLCLALSLGGTGAAPPIQ-----SRIVGGWECEQHSQPWQAALY-----HFSTFQCGGILVHR 57

  Fly    64 VTIVTAAHCLTYNQGQAVAGAHSRTDQENVQIRKFTNAQYV-IHENYGGGVGPN-DIGLILLK-- 124
            ..::|||||::.|. |...|.|:..|.||       .||:| :.|::     |: ...:.||:
Human    58 QWVLTAAHCISDNY-QLWLGRHNLFDDEN-------TAQFVHVSESF-----PHPGFNMSLLENH 109

  Fly   125 -----EEDAFDLNAV-----ARDGSNPVSAVSLPSKTFQGTSDGYLYGWG--RDNSGLLPLNLQK 177
                 |:.:.||..:     |...::.|..|.||::..:..|.....|||  ...:...|.:||.
Human   110 TRQADEDYSHDLMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQC 174

  Fly   178 LDAIIVDYNECKAALPSNNSLAETNVCT-HTPGKADGSCNGDSGGPLVSQSSSRGAELIGIVSWG 241
            :|..|:..:|||.|  ....:.:..:|. |..|..| :|.|||||||:..     ..|.|:.|||
Human   175 VDLKILPNDECKKA--HVQKVTDFMLCVGHLEGGKD-TCVGDSGGPLMCD-----GVLQGVTSWG 231

  Fly   242 YTPCLSTTYPSVYTSVSSFLPWIDE 266
            |.||.:...|||...|.|::.||::
Human   232 YVPCGTPNKPSVAVRVLSYVKWIED 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11912	NP_608517.1	Tryp_SPc	29..264	CDD:214473	76/255 (30%)
KLK1	NP_002248.1	Tryp_SPc	25..257	CDD:238113	77/258 (30%)