Protein Alignment CG11912 and KLK3

DIOPT Version :10

• Sequence 1: NP_608517.1
• Gene: CG11912 / 33205
• FlyBaseID: FBgn0031248
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: NP_001639.1
• Gene: KLK3 / 354
• HGNCID: 6364
• Length: 261
• Species: Homo sapiens
• Alignment Length: 250
• Identity: 72/250 - (28%)
• Similarity: 110/250 - (44%)
• Gaps: 30/250 - (12%)

  Fly    29 RIINGYEAAKGEAPYIVSLQTTSNSHFCAGSLLDEVTIVTAAHCLTYNQGQAVAGAHSRTDQENV 93
            ||:.|:|..|...|:.| |..:.....|.|.|:....::|||||:. |:...:.|.||....|:.
Human    24 RIVGGWECEKHSQPWQV-LVASRGRAVCGGVLVHPQWVLTAAHCIR-NKSVILLGRHSLFHPEDT 86

  Fly    94 ----QI-RKFTNAQYVIHENYGGGVGPNDIG---LILLKEEDAFDLNAVARDGSNPVSAVSLPSK 150
                |: ..|.:..|.:.......:.|.|..   |:||:..:..:|       ::.|..:.||::
Human    87 GQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAEL-------TDAVKVMDLPTQ 144

  Fly   151 TFQGTSDGYLYGWG--RDNSGLLPLNLQKLDAIIVDYNECKAALPSNNSLAETNVCT--HTPGKA 211
            .....:..|..|||  .....|.|..||.:|..::..:.|....|  ..:.:..:|.  .|.||:
Human   145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHP--QKVTKFMLCAGRWTGGKS 207

  Fly   212 DGSCNGDSGGPLVSQSSSRGAELIGIVSWGYTPCLSTTYPSVYTSVSSFLPWIDE 266
              :|:||||||||.     ...|.||.|||..||.....||:||.|..:..||.:
Human   208 --TCSGDSGGPLVC-----NGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKD 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11912	NP_608517.1	Tryp_SPc	29..264	CDD:214473	70/246 (28%)
KLK3	NP_001639.1	Tryp_SPc	25..256	CDD:238113	71/248 (29%)