DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11912 and Prss53

DIOPT Version :9

Sequence 1:	NP_608517.1	Gene:	CG11912 / 33205	FlyBaseID:	FBgn0031248	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	NP_001074737.1	Gene:	Prss53 / 330657	MGIID:	2652890	Length:	552	Species:	Mus musculus

Alignment Length:	260	Identity:	61/260 - (23%)
Similarity:	102/260 - (39%)	Gaps:	42/260 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 PGFPEGRIINGYEAAKGEAPYIVSLQTTSNSHFCAGSLLDEVTIVTAAHCLTYNQGQAVAGAHSR 87
            ||.||.:..|   ...||.|:..|:: ....|.|:|||:.:..::|||||.
Mouse    33 PGPPEPQEGN---TLPGEWPWQASVR-RQGVHICSGSLVADTWVLTAAHCF-------------- 79

  Fly    88 TDQENVQIRKFTNAQYVIH--ENYGGGVGPNDIGLILLKEEDAF-------DLNAVARDGSNPVS 143
               |.:...:.::...|:.  :..|...|..::|:..|:...|:       ||..:........:
Mouse    80 ---EKMATAELSSWSVVLGSLKQEGQSPGAEEVGVAALQLPKAYNHYSQGSDLALLQLTHPTVQT 141

  Fly   144 AVSLPSKTFQ---GTSDGYLYGWGRDNSGL------LPLNLQKLDAIIVDYNECKAALPSNNSLA 199
            .:.||..|:.   |.| .:..||.::.|.:      |.|.|.........||.....|.||.:..
Mouse   142 TLCLPQPTYHFPFGAS-CWATGWDQNTSDVSRTLRNLRLRLISRPTCNCLYNRLHQRLLSNPARP 205

  Fly   200 ETNVCTHTPGKADGSCNGDSGGPLVSQSSSRGAELIGIVSWGYTPCLSTTYPSVYTSVSSFLPWI 264
            ........||: .|.|.||||||::.:........:||:|: .:.|.....|.:.|.::....|:
Mouse   206 GMLCGGAQPGE-QGPCQGDSGGPVMCREPDGHWVQVGIISF-TSKCAQEDTPVLLTDMAVHSSWL 268

Fly 265 264
Mouse 269 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11912	NP_608517.1	Tryp_SPc	29..264	CDD:214473	56/252 (22%)
CG11912	NP_608517.1	Tryp_SPc	30..267	CDD:238113	57/253 (23%)
Prss53	NP_001074737.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..46		5/15 (33%)
		Tryp_SPc	45..271	CDD:238113	56/245 (23%)
		Tryp_SPc	311..522	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010