DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG11912 and KLK13

DIOPT Version :9

Sequence 1:NP_608517.1 Gene:CG11912 / 33205 FlyBaseID:FBgn0031248 Length:271 Species:Drosophila melanogaster
Sequence 2:NP_056411.1 Gene:KLK13 / 26085 HGNCID:6361 Length:277 Species:Homo sapiens


Alignment Length:278 Identity:79/278 - (28%)
Similarity:115/278 - (41%) Gaps:41/278 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 VIFALALASVSAIS-----VPQPGFPEGRIINGYEAAKGEAPYIVSLQTTSNSHFCAGSLLDEVT 65
            ||.:|.||....:|     |.......|.:..||.......|:..:| .......|.|.|:....
Human     7 VIASLTLALSGGVSQESSKVLNTNGTSGFLPGGYTCFPHSQPWQAAL-LVQGRLLCGGVLVHPKW 70

  Fly    66 IVTAAHCLTYNQGQAV-AGAHSRTDQE-NVQIRKFTNAQYVIHENYGGGVGP----NDIGLILLK 124
            ::||||||  .:|..| .|.|:....| ..|:|:..::  :.|..|..  .|    :|..::||:
Human    71 VLTAAHCL--KEGLKVYLGKHALGRVEAGEQVREVVHS--IPHPEYRR--SPTHLNHDHDIMLLE 129

  Fly   125 EEDAFDLNAVARDGSNPVSAVSLP----SKTFQGTSDGYLYGWGRDNSGLL--PLNLQKLDAIIV 183
            .:....|....:         :||    ::...||: ..:.|||...|..:  |..||..:..:.
Human   130 LQSPVQLTGYIQ---------TLPLSHNNRLTPGTT-CRVSGWGTTTSPQVNYPKTLQCANIQLR 184

  Fly   184 DYNECKAALPSNNSLAETNVCTHTPGKADGSCNGDSGGPLVSQSSSRGAELIGIVSWGYTPCLST 248
            ...||:...|  ..:.:..:|..|......||.||||||||...:     |.||||||..||...
Human   185 SDEECRQVYP--GKITDNMLCAGTKEGGKDSCEGDSGGPLVCNRT-----LYGIVSWGDFPCGQP 242

  Fly   249 TYPSVYTSVSSFLPWIDE 266
            ..|.|||.||.::.||.|
Human   243 DRPGVYTRVSRYVLWIRE 260

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11912NP_608517.1 Tryp_SPc 29..264 CDD:214473 68/246 (28%)
Tryp_SPc 30..267 CDD:238113 71/249 (29%)
KLK13NP_056411.1 Tryp_SPc 38..261 CDD:238113 71/247 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D433637at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

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