Protein Alignment CG11912 and F12

DIOPT Version :10

• Sequence 1: NP_608517.1
• Gene: CG11912 / 33205
• FlyBaseID: FBgn0031248
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: NP_000496.2
• Gene: F12 / 2161
• HGNCID: 3530
• Length: 615
• Species: Homo sapiens
• Alignment Length: 262
• Identity: 84/262 - (32%)
• Similarity: 118/262 - (45%)
• Gaps: 44/262 - (16%)

  Fly    29 RIINGYEAAKGEAPYIVSLQTTSNSHFCAGSLLDEVTIVTAAHC---------LTYNQGQAVAGA 84
            |::.|..|.:|..|||.:|..  ...||||||:....::|||||         ||...||....
Human   372 RVVGGLVALRGAHPYIAALYW--GHSFCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVLGQERRN- 433

  Fly    85 HSRTDQENVQIRKFTNAQYVIHENYGGGVGPNDIGLILLKEEDAFDLNAVARDGS----NP-VSA 144
            ||....:.:.:|     .|.:||.:......:|:.|:.| :|||        |||    :| |..
Human   434 HSCEPCQTLAVR-----SYRLHEAFSPVSYQHDLALLRL-QEDA--------DGSCALLSPYVQP 484

  Fly   145 VSLPSKTFQ--GTSDGYLYGWGRDNSGL--LPLNLQKLDAIIVDYNECKAALPSNNSLAETNVCT 205
            |.|||...:  .|:...:.|||....|.  ....||:.....:....|.|.....:|:....:|.
Human   485 VCLPSGAARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGSSILPGMLCA 549

  Fly   206 HTPGKADG---SCNGDSGGPLV--SQSSSRGAELIGIVSWGYTPCLSTTYPSVYTSVSSFLPWID 265
               |..:|   :|.||||||||  .|::.|...|.||:||| :.|.....|.|||.|:.:|.||.
Human   550 ---GFLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWG-SGCGDRNKPGVYTDVAYYLAWIR 610

  Fly   266 EN 267
            |:
Human   611 EH 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11912	NP_608517.1	Tryp_SPc	29..264	CDD:214473	81/257 (32%)
F12	NP_000496.2	FN2	41..88	CDD:128373
		EGF_CA	96..131	CDD:238011
		FN1	133..173	CDD:238018
		EGF	178..206	CDD:394967
		Kringle	217..295	CDD:395005
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	298..359
		Tryp_SPc	373..612	CDD:238113	82/259 (32%)