Protein Alignment CG11912 and F10

DIOPT Version :10

• Sequence 1: NP_608517.1
• Gene: CG11912 / 33205
• FlyBaseID: FBgn0031248
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: NP_000495.1
• Gene: F10 / 2159
• HGNCID: 3528
• Length: 488
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 78/260 - (30%)
• Similarity: 111/260 - (42%)
• Gaps: 41/260 - (15%)

  Fly    29 RIINGYEAAKGEAPYIVSLQTTSNSHFCAGSLLDEVTIVTAAHCLTYNQGQAVAGAHSRTDQEN- 92
            ||:.|.|...||.|:...|....|..||.|::|.|..|:||||||...:...|......|:||.
Human   234 RIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEG 298

  Fly    93 ----------VQIRKFTNAQYVIHENYGGGVGPNDIGLILLKEEDAFDLNAVARDGSNPVSAVSL 147
                      ::..:||...|..           ||.::.||....|.:|         |:...|
Human   299 GEAVHEVEVVIKHNRFTKETYDF-----------DIAVLRLKTPITFRMN---------VAPACL 343

  Fly   148 PSK-----TFQGTSDGYLYGWGRDN-SGLLPLNLQKLDAIIVDYNECKAALPSNNSLAETNVCTH 206
            |.:     |......|.:.|:||.: .|.....|:.|:...||.|.||  |.|:..:.:...|..
Human   344 PERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCK--LSSSFIITQNMFCAG 406

  Fly   207 TPGKADGSCNGDSGGPLVSQSSSRGAELIGIVSWGYTPCLSTTYPSVYTSVSSFLPWIDENRKAK 271
            ...|.:.:|.||||||.|::.... ..:.|||||| ..|.......:||.|::||.|||.:.|.:
Human   407 YDTKQEDACQGDSGGPHVTRFKDT-YFVTGIVSWG-EGCARKGKYGIYTKVTAFLKWIDRSMKTR 469

  Fly   272  271
            Human   470  469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11912	NP_608517.1	Tryp_SPc	29..264	CDD:214473	74/251 (29%)
F10	NP_000495.1	GLA	25..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:464251
		O-glycosylated at one site	183..203
		Tryp_SPc	235..464	CDD:238113	75/252 (30%)
		O-glycosylated at one site	476..485