DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11912 and St14

DIOPT Version :9

Sequence 1:	NP_608517.1	Gene:	CG11912 / 33205	FlyBaseID:	FBgn0031248	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	XP_036010597.1	Gene:	St14 / 19143	MGIID:	1338881	Length:	875	Species:	Mus musculus

Alignment Length:	253	Identity:	66/253 - (26%)
Similarity:	102/253 - (40%)	Gaps:	24/253 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 EGRIINGYEAAKGEAPYIVSLQTTSNSHFCAGSLLDEVTIVTAAHCL---------TYNQGQAVA 82
            :.|::.|..|.:||.|:.|||......|.|..||:....:|:||||.         .|....|..
Mouse   632 QARVVGGTNADEGEWPWQVSLHALGQGHLCGASLISPDWLVSAAHCFQDDKNFKYSDYTMWTAFL 696

  Fly    83 GAHSRTDQENVQIRKFTNAQYVIHENYGGGVGPNDIGLILLKEEDAFDLNAVARDGSNPVSAVSL 147
            |...::.:....:::....:.:.|.::.......||.|:.|::...:         |..|..:.|
Mouse   697 GLLDQSKRSASGVQELKLKRIITHPSFNDFTFDYDIALLELEKSVEY---------STVVRPICL 752

  Fly   148 PSKT--FQGTSDGYLYGWGR-DNSGLLPLNLQKLDAIIVDYNECKAALPSNNSLAETNVCTHTPG 209
            |..|  |......::.|||. ...|...|.|||.:..:::...|:..:|  ..:....:|.....
Mouse   753 PDATHVFPAGKAIWVTGWGHTKEGGTGALILQKGEIRVINQTTCEDLMP--QQITPRMMCVGFLS 815

  Fly   210 KADGSCNGDSGGPLVSQSSSRGAELIGIVSWGYTPCLSTTYPSVYTSVSSFLPWIDEN 267
            ....||.|||||||.|..........|:|||| ..|.....|.|||.:.....||.|:
Mouse   816 GGVDSCQGDSGGPLSSAEKDGRMFQAGVVSWG-EGCAQRNKPGVYTRLPVVRDWIKEH 872

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11912	NP_608517.1	Tryp_SPc	29..264	CDD:214473	63/246 (26%)
CG11912	NP_608517.1	Tryp_SPc	30..267	CDD:238113	64/248 (26%)
St14	XP_036010597.1	SEA	108..198	CDD:396113
		CUB	247..352	CDD:238001
		CUB	360..464	CDD:238001
		LDLa	474..506	CDD:238060
		LDLa	512..543	CDD:238060
		LDLa	545..579	CDD:238060
		LDLa	587..622	CDD:238060
		Tryp_SPc	635..872	CDD:238113	64/248 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920