Protein Alignment CG11912 and Klk1b4

DIOPT Version :10

• Sequence 1: NP_608517.1
• Gene: CG11912 / 33205
• FlyBaseID: FBgn0031248
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: NP_035045.2
• Gene: Klk1b4 / 18048
• MGIID: 97320
• Length: 256
• Species: Mus musculus
• Alignment Length: 281
• Identity: 79/281 - (28%)
• Similarity: 119/281 - (42%)
• Gaps: 51/281 - (18%)

  Fly     4 FAVIFALALASVSAISVPQPGFPEGRIINGYEAAKGEAPYIVSLQTTSNSHFCAGSLLDEVTIVT 68
            |.::| ||| |:..|....|       :......:...|:.|::. ..|.:.|.|.|||...::|
Mouse     3 FLILF-LAL-SLGGIDAAPP-------VQSQVDCENSQPWHVAVY-RFNKYQCGGVLLDRNWVLT 57

  Fly    69 AAHCLTYN-QGQAVAGAHS-RTDQENVQIRKFTNAQYVIHENYGGGVGPNDIGLILLKE-----E 126
            ||||  || :.|...|.:: ..|:.:.|.|..:.|  :.|.         |..:.||.|     |
Mouse    58 AAHC--YNDKYQVWLGKNNFLEDEPSDQHRLVSKA--IPHP---------DFNMSLLNEHTPQPE 109

  Fly   127 DAFDLNAVARDGSNP------VSAVSLPSKTFQGTSDGYLYGWGRDN--SGLLPLNLQKLDAIIV 183
            |.:..:.:....|.|      |..::||::..:..|.....|||...  ....|.:||.::..::
Mouse   110 DDYSNDLMLLRLSKPADITDVVKPITLPTEEPKLGSTCLASGWGSTTPIKFKYPDDLQCVNLKLL 174

  Fly   184 DYNECKAALPSNNSLAETNVCTHTPGKADG---SCNGDSGGPLVSQSSSRGAELIGIVSWGYTPC 245
            ...:|..|  ....:.:..:|.   |:.||   :|..||||||:....     |.||.|||..||
Mouse   175 PNEDCDKA--HEMKVTDAMLCA---GEMDGGSYTCEHDSGGPLICDGI-----LQGITSWGPEPC 229

  Fly   246 LSTTYPSVYTSVSSFLPWIDE 266
            ...|.|||||.:..|..||.|
Mouse   230 GEPTEPSVYTKLIKFSSWIRE 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11912	NP_608517.1	Tryp_SPc	29..264	CDD:214473	68/252 (27%)
Klk1b4	NP_035045.2	Tryp_SPc	13..251	CDD:238113	73/269 (27%)
		Activation peptide homolog	18..24		1/12 (8%)