Protein Alignment CG11912 and CTRB1

DIOPT Version :10

• Sequence 1: NP_608517.1
• Gene: CG11912 / 33205
• FlyBaseID: FBgn0031248
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: NP_001897.4
• Gene: CTRB1 / 1504
• HGNCID: 2521
• Length: 263
• Species: Homo sapiens
• Alignment Length: 279
• Identity: 98/279 - (35%)
• Similarity: 134/279 - (48%)
• Gaps: 46/279 - (16%)

  Fly     4 FAVIFALALASVSAISVPQPGFPEGRIINGYEAAKGEAPYIVSLQTTSNSHFCAGSLLDEVTIVT 68
            |:::.|.....|.||.....|.  .||:||.:|..|..|:.||||..:..|||.|||:.|..:||
Human    10 FSLVGAAFGCGVPAIHPVLSGL--SRIVNGEDAVPGSWPWQVSLQDKTGFHFCGGSLISEDWVVT 72

  Fly    69 AAHCLTYNQGQAVAGAHSR-TDQENVQIRK----FTNAQY-VIHENYGGGVGPNDIGLILLKEED 127
            ||||........|||...: :|:||:|:.|    |.|.:: ::..|       |||.|:.|....
Human    73 AAHCGVRTSDVVVAGEFDQGSDEENIQVLKIAKVFKNPKFSILTVN-------NDITLLKLATPA 130

  Fly   128 AFDLNAVARDGSNPVSAVSLPSK-------TFQGTSDGYLYGWGRD--NSGLLPLNLQKLDAIIV 183
            .|         |..||||.|||.       |...|:     |||:.  |:...|..||:....::
Human   131 RF---------SQTVSAVCLPSADDDFPAGTLCATT-----GWGKTKYNANKTPDKLQQAALPLL 181

  Fly   184 DYNECKAALPSNNSLAETNVCTHTPGKADGSCNGDSGGPLVSQSSSRGA-ELIGIVSWGYTPCLS 247
            ...|||.:.  ...:.:..:|....|.:  ||.||||||||.|..  || .|:||||||...| |
Human   182 SNAECKKSW--GRRITDVMICAGASGVS--SCMGDSGGPLVCQKD--GAWTLVGIVSWGSDTC-S 239

  Fly   248 TTYPSVYTSVSSFLPWIDE 266
            |:.|.||..|:..:||:.:
Human   240 TSSPGVYARVTKLIPWVQK 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11912	NP_608517.1	Tryp_SPc	29..264	CDD:214473	91/250 (36%)
CTRB1	NP_001897.4	Tryp_SPc	34..259	CDD:238113	91/253 (36%)