Protein Alignment CG11912 and KLK11

DIOPT Version :10

• Sequence 1: NP_608517.1
• Gene: CG11912 / 33205
• FlyBaseID: FBgn0031248
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Alignment Length: 296
• Identity: 81/296 - (27%)
• Similarity: 117/296 - (39%)
• Gaps: 61/296 - (20%)

  Fly     6 VIFALALASVSAISVPQPGFPEGRIINGYEAAKGEAPYIVSLQTTSNSHFCAGSLLDEVTIVTAA 70
            ::.|||...|..         |.|||.|:|......|:..:|...:.. .|..:|:....::|||
Human    39 ILLALATGLVGG---------ETRIIKGFECKPHSQPWQAALFEKTRL-LCGATLIAPRWLLTAA 93

  Fly    71 HCLTYNQGQAVAGAHSRTDQENVQIRKFTNAQYVIHENYGGGVGPNDIGLILLKEEDAFDLNAVA 135
            |||. ......:..|...|..:........::|::|      :|.::    |.|||.........
Human    94 HCLK-PWVSLTSPTHVSPDLSSSNYCLSHLSRYIVH------LGQHN----LQKEEGCEQTRTAT 147

  Fly   136 RDGSNPVSAVSLPSKTFQ------------------------------GTSDGYLYGWGRDNSG- 169
            ....:|....|||:|..:                              ||| ..:.|||..:|.
Human   148 ESFPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVTAGTS-CLISGWGSTSSPQ 211

  Fly   170 -LLPLNLQKLDAIIVDYNECKAALPSNNSLAETNVCTHTPGKADGSCNGDSGGPLVSQSSSRGAE 233
             .||..|:..:..|:::.:|:.|.|.|  :.:|.||.........||.||||||||...|
Human   212 LRLPHTLRCANITIIEHQKCENAYPGN--ITDTMVCASVQEGGKDSCQGDSGGPLVCNQS----- 269

  Fly   234 LIGIVSWGYTPCLSTTYPSVYTSVSSFLPWIDENRK 269
            |.||:|||..||..|..|.|||.|..::.||.|..|
Human   270 LQGIISWGQDPCAITRKPGVYTKVCKYVDWIQETMK 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11912	NP_608517.1	Tryp_SPc	29..264	CDD:214473	72/266 (27%)
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	72/266 (27%)