Protein Alignment Plc21C and plcl5

DIOPT Version :9

• Sequence 1: NP_995605.1
• Gene: Plc21C / 33204
• FlyBaseID: FBgn0004611
• Length: 1318
• Species: Drosophila melanogaster
• Sequence 2: XP_002661169.2
• Gene: plcl5 / 327464
• ZFINID: ZDB-GENE-030131-5675
• Length: 1122
• Species: Danio rerio
• Alignment Length: 1086
• Identity: 275/1086 - (25%)
• Similarity: 440/1086 - (40%)
• Gaps: 285/1086 - (26%)

  Fly    25 KFIRWDDDSGTGTPVTMRVDAKGFFLYWVDQNNELDILDIATIRDVRTGQYAKRPKDNKLRQIVT 89
            :::||:...                     :::|...|:|.:|::||.|:.....:.|
Zfish   158 RWLRWEPSK---------------------KDSEKAKLEIKSIKEVRLGKKTPVLRSN------- 194

  Fly    90 LGPQDTL-EEKTVTVCHGSDFVNMTFVNFCCTRRDIAQLWTDGLIKLAYSLAQLNGSAIMFLQKA 153
             |..|.. ||...::.:|.::.::..|   .:..|:...|..||..|......:.|.|.......
Zfish   195 -GLSDQFPEECAFSIIYGDNYESLDLV---ASTADVVSTWVMGLRYLVSYGRHMVGVAEPSQPSV 255

  Fly   154 HTKLCLQV------DKSGRIPV---KNIIK-LFAQNKEDR-----KRVEKALDVTGLPSGKVDSI 203
            .|.....|      ::.|.|.:   ..||| |....:|.|     |.::||.|..|
Zfish   256 RTSWIGSVFDLADPERQGHIDLFRATQIIKGLNPGMRESRIELKFKELQKAKDCYG--------- 311

  Fly   204 SVSKFQFEDFYNLYKYLTQRSEVERLFDSIVGNSKRKCMSIAQLVEFLNKTQRDPRLNEILYPYA 268
              .....:.|...|..|..|||:  .|..:..:|.::.:....|:.|:...|....:.|.:
Zfish   312 --EGIDLDTFVEAYCELCTRSEI--FFLLVQFSSNKEYLDSKDLMIFVEVEQGVEGVTEEM---- 368

  Fly   269 NPARAKELIQQYEPNKFNAQKGQLSLDGFLRYLMGDDNPIMAPSKLDLCDDMDQPMSHYFINSSH 333
                .:|::.:|||:......|.||:|||..||:..:..|..|....:|.||.||:|||:|||||
Zfish   369 ----CREIVHKYEPSAEGRNNGYLSIDGFTHYLLSSECHIFDPQHKHVCQDMTQPLSHYYINSSH 429

  Fly   334 NTYLTGHQLTGKSSVEIYRQCLLAGCRCVELDFWNGRTEEPVIVHGYTFVPEIFAKDVLEAIAES 398
            |..|......|.|.:..|.:.|..|||.:|:..|:|...|||:..|.:...::....:|:.|.:.
Zfish   430 NASLLEDHYWGSSDLSSYVRALRMGCRSLEVVVWDGPDCEPVVYVGSSVASQLAFCKILDVINQY 494

  Fly   399 AFKTSEYPVILSFENHCNPRQQAKIANYCREIFGDMLLDKPLDSHPLEPNMD---LPPPAMLRRK 460
            ||::||||:||....||:..||..:|.:.::|.||.|       |...||::   ||.|..|:.|
Zfish   495 AFESSEYPLILCLVTHCSVPQQRVMAQHLKKILGDKL-------HIESPNLEDHYLPSPDKLKGK 552

  Fly   461 IIIKNKKKHHHHHHHHHHKKPAQVGTPAANNKLTTANSVDAKAA---QQVGLSASHEDGGVTRST 522
            ::||.|                         :|.| :|.|::..   ::.|...|....||.
Zfish   553 VLIKGK-------------------------RLPT-DSQDSEGEVTDEEEGFEMSRRMMGVD--- 588

  Fly   523 ANGDVATGTGTGSAAGTAGHAPPLQQIRQSSKDSTGSSDSDSSSEDESLPNTTPNLPSGNEPPPE 587
             :.|...|.|.
Zfish   589 -DKDHLNGIGC------------------------------------------------------ 598

  Fly   588 KAQKETEAGAEISALVNYVQPIHFSSFENAEKKNRCYEMSSFDEKQATTLLKERPIEFVNYNKHQ 652
               |......|:|.||...:.:.|..||.::::.:.:|:.||:|..|.....|.|.:||:|||..
Zfish   599 ---KRLRLCKELSDLVTLCKSVQFRDFEMSKREQKHWEICSFNEVDANRFANEFPEDFVSYNKRF 660

  Fly   653 LSRVYPAGTRFDSSNFMPQLFWNAGCQLVALNFQTLDLAMQLNLGIFEYNARSGYLLKPEFMRRS 717
            ||||||...|.|:||..||.||..|||:||:|:||..|.|.||||.|..|...||:|:|..||..
Zfish   661 LSRVYPTPMRIDASNMNPQDFWKCGCQIVAMNYQTPGLMMDLNLGWFRQNGNCGYVLRPAIMREE 725

  Fly   718 DRRLDPFAESTVDGIIAGTVSITVLSGQFLTDKRANT--------FVEVDMYGLPADTVRKKFRT 774
            .......|..::.|:.|..:.|.|:|||.|...|.:.        ::.|:::|:|||...:  ||
Zfish   726 VSYFSANARDSLPGVSAQLLHIKVISGQNLPKPRGSAAKGDVVEPYIYVEIHGIPADCAEQ--RT 788

  Fly   775 KTVRDNGMNPLYDEEPFVFKKVVLPELASIRIAAYEE---GGKLIGHRVLPVIGLCPGYRHVNLR 836
            |||..||.||::||. |.| ::.|||||.:|....::   |.:.||...:|...|.||||||.|:
Zfish   789 KTVSQNGDNPIFDES-FEF-QINLPELAVLRFVVLDDDYIGDEFIGQYTIPFECLLPGYRHVPLQ 851

  Fly   837 SEVGQPIALASLFLCVVV----------------------KDY---------VPDDLSNFAEALA 870
            |..|:.:...:||:.|.:                      ::|         |.|:|   ..|..
Zfish   852 SLTGEFLPNTTLFVHVAITNRRGGGKAHKRGLSVRKGRKAREYTSTKTTGIKVVDEL---FRAST 913

  Fly   871 NPIKYQSELEKR------------------DIQLSVLTDEAEALGS-----ADEDLSKSFVFVQV 912
            .|::..::|.:.                  :::..:||..:..:.|     ...|||:::..::.
Zfish   914 QPLREATDLRENVQNAMVSFKELCGLTPAANMKQCILTVSSWLMNSERVLRVTVDLSEAYPTMEA 978

  Fly   913 GGQKKELRPVESLATSPKHRPSISAAAAMSVDVTVDRTDGGRGEDSISIVAPSIQHQHSLDQS-- 975
            .|      |:..|.     |..::|...|                        ||...:|.:|
Zfish   979 HG------PIPELL-----RKVLTAYDTM------------------------IQTSRTLIESAD 1008

  Fly   976 -VSTSIRQVESSQFDVDLVLAEPLEKILDHKSVKEKRLEMEKKLES 1020
             |.:.:.|.:.:..|    ..|.|.:|...:.:|.::|  :|.:||
Zfish  1009 GVYSKLTQAQRAGLD----FHEDLHRIGAREGLKGRKL--QKAMES 1048

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Plc21C	NP_995605.1	PH_PLC_beta	20..145	CDD:270167	21/120 (18%)
		PLN02222	213..850	CDD:177868	201/653 (31%)
		EF-hand_like	225..317	CDD:286375	21/91 (23%)
		PI-PLCc_beta	317..702	CDD:176533	119/390 (31%)
		C2_PLC_like	736..855	CDD:175974	48/151 (32%)
plcl5	XP_002661169.2	PH	131..239	CDD:278594	21/112 (19%)
		PH_PLC_eta	131..239	CDD:270170	21/112 (19%)
		PLN02228	324..872	CDD:177873	201/655 (31%)
		EF-hand_like	331..413	CDD:286375	21/91 (23%)
		PI-PLCc_PRIP_metazoa	413..710	CDD:176539	119/390 (31%)
		C2_PLC_like	742..870	CDD:175974	49/131 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586431
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0169
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D368239at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.750