Protein Alignment Plc21C and plcl2

DIOPT Version :9

• Sequence 1: NP_995605.1
• Gene: Plc21C / 33204
• FlyBaseID: FBgn0004611
• Length: 1318
• Species: Drosophila melanogaster
• Sequence 2: XP_002667725.3
• Gene: plcl2 / 100334276
• -ID: -
• Length: 1097
• Species: Danio rerio
• Alignment Length: 1119
• Identity: 296/1119 - (26%)
• Similarity: 477/1119 - (42%)
• Gaps: 266/1119 - (23%)

  Fly    43 VDAKGFFLYWVDQNNELD--ILDIATIRDVRTGQYAKRPKDNKLRQIVTLGPQDTLEEKTVTVCH 105
            :||....|.|.....|.|  .:|:.:|::||||:.....:.|.:...::       |:...::.:
Zfish   128 LDADMQSLRWEPSKKESDKAKIDVKSIKEVRTGKNTDTFRTNGISDQIS-------EDCAFSIIY 185

  Fly   106 GSDFVNMTFVNFCCTRRDIAQLWTDGL-IKLAYSLAQLNGSAIMFLQKAHT--------KLCLQV 161
            |.::.::..|   ....|:|.:|..|| ..::|....||     .:|.:..        :|..:.
Zfish   186 GENYESLDLV---ANSADVANIWVTGLRYLISYGKHTLN-----MIQSSQDNMRASWLGELFDEA 242

  Fly   162 DKSGR--IPVKNIIKLFAQNKEDRKRVEKALDVTGLPSGKVDSIS-VSKFQFEDFYNLYKYLTQR 223
            |..||  |.:...::|..:.....|.|:..|....|...|..|.| |:|   |:|..::..|..|
Zfish   243 DAIGRKSISLCTAVQLIKKLSPGVKNVKIELKFKELHKSKDKSSSDVTK---EEFIEVFHDLCTR 304

  Fly   224 SEVERLFDSIVGNSKRKCMSIAQLVEFLNKTQRDPRLNEILYPYANPARAKELIQQYEPNKFNAQ 288
            .|:  .|..:..:|.::.:....|:.||...|...:::|.:        :.|:||:|||:|....
Zfish   305 PEI--YFLLVQFSSNKEFLDTKDLMIFLEAEQGMAKVSEDI--------SVEVIQKYEPSKEGQL 359

  Fly   289 KGQLSLDGFLRYLMGDDNPIMAPSKLDLCDDMDQPMSHYFINSSHNTYLTGHQLTGKSSVEIYRQ 353
            ||.||||||..|||..|..|..|.:..:|.||:||:|||:|||||||||...|..|.|.:..|.:
Zfish   360 KGWLSLDGFTNYLMSADCHIFDPEQKTVCQDMNQPLSHYYINSSHNTYLIEDQFRGPSDITGYIR 424

  Fly   354 CLLAGCRCVELDFWNGRTEEPVIVHGYTFVPEIFAKDVLEAIAESAFKTSEYPVILSFENHCNPR 418
            .|..|||.||||.|:|...||||..|:|...:|..::|::.|.:.||..||:|:.|..||||:.:
Zfish   425 ALKMGCRSVELDVWDGPDNEPVIYTGHTMTSQIVFRNVIDIINKYAFAASEFPLFLCLENHCSLK 489

  Fly   419 QQAKIANYCREIFGDMLLDKPLDSHPLEPNMD---LPPPAMLRRKIIIKNKKKHHHHHHHHHHKK 480
            ||..|..:.::|.||.:       |...||::   ||.|..|:.||::|.|            |.
Zfish   490 QQKVIFQHLKKILGDKV-------HTDPPNLEDNYLPSPLDLKGKILLKGK------------KL 535

  Fly   481 PAQVGTPAANNKLTTANSVDAKAAQQVGLSASHEDGGVTRSTANGDVATGTGTGSAAGTAGHAPP 545
            |:....|                           :|.||
Zfish   536 PSNCTEP---------------------------EGEVT-------------------------- 547

  Fly   546 LQQIRQSSKDSTGSSDSDSSSEDESLPNTTPNLPSGNEPPPEKA---QKETEAGAEISALVNYVQ 607
                           |.|..:|.....|        ||...::.   .|:.:...::|.||...:
Zfish   548 ---------------DEDEGAEMSQRMN--------NEASEQQVVVQPKKFQLSKDLSDLVTLCK 589

  Fly   608 PIHFSSFENAEKKNRCYEMSSFDEKQATTLLKERPIEFVNYNKHQLSRVYPAGTRFDSSNFMPQL 672
            .:.|..|:.|.:..:.:|:.||:|..|:....:.|.:||||||..|:||||:..|.||||..||.
Zfish   590 SVQFKDFQMAFQNQKHWELCSFNEVFASRCATDHPGDFVNYNKKFLARVYPSPMRIDSSNMNPQD 654

  Fly   673 FWNAGCQLVALNFQTLDLAMQLNLGIFEYNARSGYLLKPEFMRRSDRRLDPFAESTVDGIIAGTV 737
            ||..|||:||:|:||..|.|.||:|.|..|...||:|:|..||..........:.:|.|:....:
Zfish   655 FWKCGCQIVAMNYQTPGLMMDLNIGWFRQNGNCGYVLRPAIMREQVSYFSANTKDSVPGVSPQLL 719

  Fly   738 SITVLSGQFLTDKR--------ANTFVEVDMYGLPADTVRKKFRTKTVRDNGMNPLYDEEPFVFK 794
            .|.::||..|...:        .:.:|.|:::|:|||...:  |||||..||.||::||. |.|
Zfish   720 HIKIISGLNLPKPKGSGAKGDVVDPYVYVEIHGIPADCAEQ--RTKTVHQNGDNPIFDES-FEF- 780

  Fly   795 KVVLPELASIRIAAYEE---GGKLIGHRVLPVIGLCPGYRHVNLRSEVGQPIALASLFLCVVV-- 854
            ::.|||||.:|....::   |.:.||...:|...:.||:||:.|:|..|:.:..|.:|:.|.:
Zfish   781 QINLPELAMVRFVVLDDDYIGDEFIGQYTIPFECIQPGFRHIPLQSLTGEVLPHAWVFVHVAITN 845

  Fly   855 --------------------KDYVP---------DDLSNFAEALANPIKYQSELEKRDIQLSVLT 890
                                ::|..         |::...|   |.|::..::|  |:...:.:.
Zfish   846 RRGGGKPHKRGLSVRKGKRGREYASMRILLIKAVDEVFKSA---AQPLREATDL--RENMQNAIV 905

  Fly   891 DEAEALG-SADEDLSKSFVFVQVGGQKKELRPVESLATSPK----------------HRPSISAA 938
            ...|..| ||..:|.:..                 ||.||:                ..||:.|.
Zfish   906 PFKELCGLSAVANLKQCI-----------------LALSPRLIGPDGSPFLLFNLREQYPSVEAQ 953

  Fly   939 A--------AMSVDVTVDRTDGGRGEDSISIVAPSIQ--------HQHSLDQSVSTSI------R 981
            :        |::...|:.:|.....|:|..:....:|        |::..|.:|...:      :
Zfish   954 SLLPEVLKRAVTAYDTMIQTSQALLENSDGVYDRILQVQKAAMEFHENLHDMAVKEGLKGRKLHK 1018

  Fly   982 QVESSQFDVDLVLAEPLEKILDHKSVKEKRLEMEKKLESLRKKH------DKEKIKIAGQKSSPL 1040
            .|||..:::.::..:.       ..:|..|.|:   ||:|::.|      :..|........|..
Zfish  1019 SVESFTWNITILKGQA-------DLLKHARAEV---LENLKQIHYAALTCNLAKGGAGPSSGSES 1073

  Fly  1041 EGKKPKFAITNKLV 1054
            .|::...||..|.|
Zfish  1074 RGRRSLEAIPEKAV 1087

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Plc21C	NP_995605.1	PH_PLC_beta	20..145	CDD:270167	24/104 (23%)
		PLN02222	213..850	CDD:177868	208/653 (32%)
		EF-hand_like	225..317	CDD:286375	29/91 (32%)
		PI-PLCc_beta	317..702	CDD:176533	126/390 (32%)
		C2_PLC_like	736..855	CDD:175974	43/151 (28%)
plcl2	XP_002667725.3	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D368239at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920