Sequence 1: | NP_001259817.1 | Gene: | Pi3K21B / 33203 | FlyBaseID: | FBgn0020622 | Length: | 496 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_005018.2 | Gene: | PIK3R2 / 5296 | HGNCID: | 8980 | Length: | 728 | Species: | Homo sapiens |
Alignment Length: | 445 | Identity: | 159/445 - (35%) |
---|---|---|---|
Similarity: | 222/445 - (49%) | Gaps: | 62/445 - (13%) |
- Green bases have known domain annotations that are detailed below.
Fly 3 PQA-PGSLVDPN---EDELRMAPWYWGRISREEAKSILHGKPDGSFLVRDALS-MKGEYTLTLMK 62
Fly 63 DGCEKLIKICHMDRKYGFIETDLFNSVVEMINYYKENSLSMYNKTLDITLSNPIVRAREDEESQP 127
Fly 128 HGDLCLLSNEFIRTC-QLLQNLEQNLENKRNSFNAIRE-------ELQEKKLHQSVFGNTEKIFR 184
Fly 185 NQIKLNESFMKAPADAPSTEAGGAGDGANAAASAAANANARRSLQEHKQTLLNLLDALQAKGQVL 249
Fly 250 NHYMENKKKEELL---------LERQINALKPELQILQLRK--DKYIERL--KGFNLKDDDLKMI 301
Fly 302 LQMGFDKWQQLYETVSNQPHSNEALWLLKDAKRRNAEEMLKGAPSGTFLIR-ARDAGHYALSIAC 365
Fly 366 KNIVQHCLIYETSTGFGFAAPYNIYATLKSLVEHYANNSLEEHNDTLTTTLRWPV 420 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Pi3K21B | NP_001259817.1 | SH2_nSH2_p85_like | 14..123 | CDD:198195 | 56/109 (51%) |
PI3K_P85_iSH2 | 129..302 | CDD:293063 | 41/193 (21%) | ||
iSH2_PI3K_IA_R | 138..303 | CDD:304922 | 41/185 (22%) | ||
SH2_cSH2_p85_like | 320..422 | CDD:198184 | 53/102 (52%) | ||
PIK3R2 | NP_005018.2 | SH3_PI3K_p85beta | 7..80 | CDD:212842 | |
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 81..117 | ||||
RhoGAP | 110..296 | CDD:295372 | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 254..279 | ||||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 295..320 | 6/12 (50%) | |||
SH2_nSH2_p85_like | 322..432 | CDD:198195 | 56/109 (51%) | ||
iSH2_PIK3R2 | 437..597 | CDD:214019 | 41/185 (22%) | ||
SH2_cSH2_p85_like | 615..717 | CDD:198184 | 53/102 (52%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 1 | 0.930 | - | - | C165144341 | |
Domainoid | 1 | 1.000 | 95 | 1.000 | Domainoid score | I7410 |
eggNOG | 1 | 0.900 | - | - | E1_KOG4637 | |
Hieranoid | 1 | 1.000 | - | - | ||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 1 | 1.050 | 227 | 1.000 | Inparanoid score | I3483 |
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 1 | 1.010 | - | - | D323393at33208 | |
OrthoFinder | 1 | 1.000 | - | - | FOG0001513 | |
OrthoInspector | 1 | 1.000 | - | - | otm40387 | |
orthoMCL | 1 | 0.900 | - | - | OOG6_103810 | |
Panther | 1 | 1.100 | - | - | O | PTHR10155 |
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 1 | 1.000 | - | - | X1082 | |
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 1 | 0.960 | - | - | ||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
13 | 12.760 |