DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pi3K21B and Socs16D

DIOPT Version :9

Sequence 1:	NP_001259817.1	Gene:	Pi3K21B / 33203	FlyBaseID:	FBgn0020622	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_001259662.1	Gene:	Socs16D / 32760	FlyBaseID:	FBgn0030869	Length:	1021	Species:	Drosophila melanogaster

Alignment Length:	176	Identity:	42/176 - (23%)
Similarity:	79/176 - (44%)	Gaps:	26/176 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 WYWGRISREEAKSILHGKPDGSFLVRDALSMKGEYTLTLMKDGCEKLIKICHMDRKYGFIETDLF 86
            ||||.:|.|.|:.:|..:|||||:|||:......::|:...:.|.:.::|......:.|.....|
  Fly   850 WYWGPLSSEAAEKVLSSEPDGSFIVRDSSDDHYIFSLSFKLNNCVRHVRIEQDQGTFSFGSYAKF 914

  Fly    87 NS--VVEMINYYKENSLS------MYNK----TLDITLSNPIVRAREDEESQPHGDLC------- 132
            .|  :.|.|....|:|.|      ::.:    .:.:.|:||:.|.:..:..|   .:|
  Fly   915 KSQTITEFIEKAVEHSRSGRYLFFLHRRPEHGPMRVQLTNPVSRFKHVQSLQ---HMCRFVILKA 976

  Fly   133 LLSNEFIRTCQLLQNLEQNLENKRNSFNAIREELQEKKLHQSVFGN 178
            ::..:.|:|..|.:.|...|..|    :...|:::....|..:.|:
  Fly   977 VIRKDLIQTLPLPRRLLDYLNYK----HCYSEQVESDSSHSQISGD 1018

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pi3K21B	NP_001259817.1	SH2_nSH2_p85_like	14..123	CDD:198195	31/112 (28%)
		PI3K_P85_iSH2	129..302	CDD:293063	10/57 (18%)
		iSH2_PI3K_IA_R	138..303	CDD:304922	9/41 (22%)
		SH2_cSH2_p85_like	320..422	CDD:198184
Socs16D	NP_001259662.1	SH2_SOCS7	839..937	CDD:198251	27/86 (31%)
Socs16D	NP_001259662.1	SOCS_SOCS7	960..1009	CDD:239710	9/55 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10155
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010