DRSC/TRiP Functional Genomics Resources

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Protein Alignment Stip1 and Sugt1

DIOPT Version :9

Sequence 1:NP_477354.1 Gene:Stip1 / 33202 FlyBaseID:FBgn0024352 Length:490 Species:Drosophila melanogaster
Sequence 2:NP_080750.1 Gene:Sugt1 / 67955 MGIID:1915205 Length:336 Species:Mus musculus


Alignment Length:340 Identity:74/340 - (21%)
Similarity:128/340 - (37%) Gaps:58/340 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    23 AVAAYTEAIALDDQNHVLYSNRSAAFAKAGKFQEALEDAEKTIQLNPTWPKGYSRKGAAAAGLND 87
            |:...|:|:..:..:...|..|:......||:::.:.|.:|:::|||.......|||.......|
Mouse    30 ALEELTKALEQNPDDAQYYCQRAYCHILLGKYRDGIADVKKSLELNPNNCTALLRKGICEYHEKD 94

  Fly    88 FMKAFEAYNEGLKYDPTNAIL---------LQGRMETTASALSFMQSQGDIPMDVDPQQARSRRA 143
            :..|.|.:.||.|.|.|:...         :|...|:..||....||:    :..|..|..|...
Mouse    95 YASALETFAEGQKLDSTDTNFDTWIKRCQEIQNGSESEVSASQRTQSK----IKYDWYQTESHVI 155

  Fly   144 PSPPPAKPAEPPKPAEPRVEDMTEE-QKNKY-FARKEKELGNAAYK---KKDFETALKHYHAAIE 203
                              :..|.:. |||.. ....|:|| :|..|   .:|:...|:..|..| 
Mouse   156 ------------------ITLMIKSVQKNDVRVGFSEREL-SALVKIPAGEDYSLKLRLLHPII- 200

  Fly   204 HDPTDITFYNNIAAVHFERKEYEECIKQCEKGIEVGRESRADFKLIAKSFARIGNTYRKLENYKQ 268
              |...||  .:.:...|.|..:....:.||     .|.:.|.....:..|.:.|.|....:|.:
Mouse   201 --PEQSTF--KVLSTKIEIKMKKPEAVRWEK-----LEGQGDEPTPKQFTADVKNMYPSSSHYTR 256

  Fly   269 AKVYYEKAMSEHRTPEIKTSLSEVEAKIKEEERMAYINPEKAEEEKEQGNLFFKKGDYSTAVKHY 333
               .::|.:.|.:..| |....|.:|.:.:..:..|  .:.::|.|...|..|.:...:....::
Mouse   257 ---NWDKLVGEIKEEE-KNEKLEGDAALNKLFQQIY--SDGSDEVKRAMNKSFMESGGTVLSTNW 315

  Fly   334 TEAIKRN-----PDD 343
            ::..||.     |||
Mouse   316 SDVGKRKVEINPPDD 330

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Stip1NP_477354.1 TPR_11 6..69 CDD:290150 10/45 (22%)
TPR repeat 7..32 CDD:276809 3/8 (38%)
TPR repeat 37..67 CDD:276809 6/29 (21%)
TPR_11 40..103 CDD:290150 18/62 (29%)
TPR repeat 72..100 CDD:276809 8/27 (30%)
TPR_11 175..237 CDD:290150 16/64 (25%)
TPR repeat 175..203 CDD:276809 8/30 (27%)
TPR_1 181..208 CDD:278916 8/29 (28%)
TPR_12 205..278 CDD:290160 14/72 (19%)
TPR repeat 208..238 CDD:276809 6/29 (21%)
TPR repeat 250..278 CDD:276809 5/27 (19%)
TPR_1 250..>276 CDD:278916 4/25 (16%)
TPR_11 309..375 CDD:290150 9/40 (23%)
TPR repeat 310..338 CDD:276809 4/27 (15%)
TPR_1 <317..343 CDD:278916 5/30 (17%)
TPR repeat 343..373 CDD:276809 1/1 (100%)
TPR_1 378..411 CDD:278916
TPR repeat 378..406 CDD:276809
STI1 439..478 CDD:128966
Sugt1NP_080750.1 TPR 1 11..44 3/13 (23%)
PLN03088 21..336 CDD:215568 74/340 (22%)
Motor_domain <38..>107 CDD:277568 17/68 (25%)
TPR repeat 44..74 CDD:276809 6/29 (21%)
TPR 2 45..78 9/32 (28%)
TPR 45..78 CDD:197478 9/32 (28%)
TPR 3 79..112 10/32 (31%)
TPR repeat 79..107 CDD:276809 8/27 (30%)
p23_CS_hSgt1_like 146..229 CDD:107239 23/111 (21%)
SGS 256..336 CDD:282811 16/81 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0548
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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